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https://www.researchgate.net/publication/328265448_PROTEIN_AND_PEPTIDE_DRUG_DELIVERY_SYSTEM
Protein and Peptide drug delivery system are the Novel drug Delivery System. Proteins and peptides are the most abundant components of biological cells.
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/protein-drug-delivery
Formulation of protein and peptide drugs, their route of administration, rate, and overall pharmacokinetic profile in the body are pivotal factors in deciding the success of protein drug delivery. Until the 1950s, the oral route of drug delivery was the most preferred, …
https://www.mdpi.com/1996-1944/3/3/1928/pdf
controlled, immediate or pulsed release. Release can be obtained with different particulate drug delivery systems [5]. Liposomes, solid-lipid nanoparticles, polymeric nanoparticles and virosomes are the most commonly used nanocarriers for protein delivery.Author: Roberto Solaro, Federica Chiellini, Antonella Battisti
https://www.sciencedirect.com/science/article/pii/B9780128179093000169
Mucoadhesive systems have been widely investigated in the last decade as oral drug delivery systems. The general concept of mucoadhesive drug delivery systems is to use the bioadhesion phenomenon in which certain components of the systems (usual polymers) form adhesion bonds with the mucosal membrane at the site of absorption.Author: Pran Kishore Deb, Omar Al-Attraqchi, Balakumar Chandrasekaran, Anant Paradkar, Rakesh K. Tekade
https://www.semanticscholar.org/paper/Protein-Nanoparticles-as-Drug-Delivery-Carriers-for-Lohcharoenkal-Wang/f908c9fbab7fdf43f13d544b0a5ece62f1d021ef
In this paper, we review the most significant advancements in protein nanoparticle technology and their use in drug delivery arena. We then examine the various sources of protein materials that have been used successfully for the construction of protein nanoparticles as well as their methods of preparation.
https://www.researchgate.net/publication/284171142_Nanostructures_for_protein_drug_delivery
We further classified and discussed the entries according to protein function, drug delivery, route of administration and types of excipient (freeze-dried forms). In addition, alternative choices ...
https://www.cell.com/trends/biotechnology/pdf/S0167-7799(98)01186-X.pdf
The development of site-specific drug-delivery systems for protein and peptide biopharmaceuticals Dean K. Pettit and Wayne R. Gombotz The desire to deliver protein and peptide biopharmaceuticals conveniently and effectively has led to intense investigation of site-specific drug-delivery systems.
https://bsnbiotech.files.wordpress.com/2010/10/bsnebulletin_vol2_2.pdf
Protein or Peptide drugs: Applications, Problems and Solutions Pawan Dulal 1 1University of Nottingham, UK It has always been an aspiration for a pharmaceutical company to create a drug that would be ideal with high specificity, high affinity, solubility and …
https://innovareacademics.in/journal/ijcpr/Issues/Vol3Issue2/286.pdf
Barriers (1)to protein drug delivery: Enzymatic barrier Limits absorption of protein drugs from G.I. tract. Intestinal epithelial barrier Involved in the transport of protein drugs across the intestinal epithelium. Capillary endothelial barrier Involved in transport of protein drugs across the capillary
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956587/
Barriers to oral delivery. Oral delivery is the preferred route of drug administration, as the majority of patients see it as the most convenient way to take their drugs [].Drugs taken by the oral route have the highest level of patient compliance due to the ease and simplicity of taking medications [11,12].Despite the large number of protein therapeutics being discovered each year, oral ...Author: Benjamin J Bruno, Geoffrey D Miller, Carol S Lim
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