Protein Drug Delivery Oral

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(PDF) Protein and Peptide Drug Delivery: Oral Approaches

    https://www.researchgate.net/publication/40834786_Protein_and_Peptide_Drug_Delivery_Oral_Approaches
    Designing means to deliver peptide and protein drugs successfully to the systemic circulation by the oral route has been a challenge to scientists in drug delivery for many years [1].

Nanoparticles: Oral Delivery for Protein and Peptide Drugs ...

    https://link.springer.com/article/10.1208/s12249-019-1325-z
    May 20, 2019 · Protein nanocrystallization is a new kind of oral drug delivery system. Protein nanoparticles with a particle size of 50–500 nm are formed by crystallization technology, and stable nanoparticles are formed by charge or space stabilization of surfactants.

protein and peptide drug delivery system

    https://www.slideshare.net/BrajeshKumar67/protein-and-peptide-drug
    May 24, 2015 · protein and peptide drug delivery system 1. PROTEIN AND PEPTIDE DRUG DELIVERY SYSTEM PRESENTED BY BRAJESH KUMAR M. PHARM (1ST YEAR) PHARMACEUTICS BBAU LUCKNOW , 1 2. Contents I. Protein & Peptides II. Structure of protein III. Classification of protein IV. Drug delivery system V. Stability testing VI. Conclusion VII. References 2 3.

(PDF) An over view: Protein and peptide based drug delivery

    https://www.researchgate.net/publication/319122467_An_over_view_Protein_and_peptide_based_drug_delivery
    The main barriers to ef fective oral delivery a re- ... possible for peptide and protein drug delivery, Elsevier, 11, 2016, 905-910. 11. Kyeongsoon Park, Ick Chan Kwon, Kinam Park, Oral protein .

Advances in oral peptide therapeutics Nature Reviews ...

    https://www.nature.com/articles/s41573-019-0053-0
    Dec 17, 2019 · Oral delivery of peptide therapeutics could have benefits for treatment adherence, but it faces barriers related to the structural organization and physiological function of the gastrointestinal ...

Oral drug delivery of proteins - YouTube

    https://www.youtube.com/watch?v=IamdkBcQH0Q
    Apr 28, 2016 · suggested design for modification of solid lipid nano-particles modified by stearic acid octaarginine for oral drug delivery of proteins.Author: samar yousef

Bioadhesive Food Protein Nanoparticles as Pediatric Oral ...

    https://pubs.acs.org/doi/10.1021/acsami.9b00152
    The goal of this study was to develop bioadhesive food protein nanoparticles using zein (Z), a hydrophobic corn protein, as the core and whey protein (WP) as the shell for oral pediatric drug delivery applications. Lopinavir (LPV), an antiretroviral drug, and fenretinide, an investigational anticancer agent, were used as model drugs in the study.

Drug delivery - Wikipedia

    https://en.wikipedia.org/wiki/Drug_delivery
    Drug delivery is often approached via a drug's chemical formulation, but it may also involve medical devices or drug-device combination products. Drug delivery is a concept heavily integrated with dosage form and route of administration, the latter sometimes even being considered part of the definition.

Protein Based Nanostructures for Drug Delivery

    https://www.hindawi.com/journals/jphar/2018/9285854/
    The development of nanoparticles drug delivery system is accepted to play major role in treatment of various life-threatening diseases as it provides safe, effective, and stable therapeutics effects, whereas protein nanoparticles hold promising results in nasal, pulmonary, oral, and ocular delivery, nonviral gene delivery, blood brain barrier ...

MucuJet: Oral Protein Drug Delivery System - Available ...

    https://techtransfer.universityofcalifornia.edu/NCD/24189.html
    Innovative large-molecule medicines face daunting limitations to benefit patients due to problems with delivery to the body. Current oral delivery of protein-based drugs, such as insulin, are denatured by digestive enzymes and suffer from poor gastrointestinal mucus permeability, which leads to unacceptably low drug bioavailability and therapeutic efficacy.

AN INNOVATIVE SMART ORAL DELIVERY TECHNOLOGY FOR …

    https://www.ondrugdelivery.com/innovative-smart-oral-delivery-technology-proteins-peptides/
    Evonik's drug delivery related activities take place within the Healthcare business line of The Nutrition & Care segment, and include functional pharmaceutical excipients, drug delivery technologies, development services, and GMP manufacturing for oral and parenteral formulations.

Non-invasive delivery strategies for biologics Nature ...

    https://www.nature.com/articles/nrd.2018.183
    Nov 30, 2018 · A review of advanced oral drug delivery technologies facilitating the protection and absorption of protein and peptide molecules. Biotechnol. Adv. 32 , 1269–1282 (2014).

The oral delivery of protein and peptide drugs

    http://www.iptonline.com/articles/public/IPTNINE106NoPrint.pdf
    DRUG FORMULATION & DELIVERY The oral delivery of protein and peptide drugs A variety of strategies can be used to overcome the barriers to protein/ peptide drug delivery by the oral route. Dr Richard Soltero and Dr Nnochiri Ekwuribe, Nobex Corporation T he use of polypeptides and proteins for systemic treatment of certain diseases is

Self-emulsifying drug delivery systems in oral (poly ...

    https://www.tandfonline.com/doi/abs/10.1517/17425247.2015.1068287
    Introduction: Oral administration of most therapeutic peptides and proteins is mainly restricted due to the enzymatic and absorption membrane barrier of the GI tract. In order to overcome these barriers, various technologies have been explored. Among them, self-emulsifying drug delivery systems (SEDDS) received considerable attention as potential carriers to facilitate oral peptide and protein ...

Bone-building protein delivered orally to mice using ...

    https://www.nih.gov/news-events/nih-research-matters/bone-building-protein-delivered-orally-mice-using-plants
    Diabetic mice fed plants engineered to carry a bone-building protein showed accelerated healing of bone fractures. The proof-of-concept study adds to recent findings showing that plants can be used to deliver protein-based drugs safely from the mouth to the bloodstream. Modern technology has ...

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