We have collected information about Protamine Sirna Delivery for you. Follow the links to find out details on Protamine Sirna Delivery.
https://www.sciencedirect.com/science/article/pii/S2211383517303465
For siRNA delivery, the biomimetic systems are generally divided into two major types based on viral and non-viral vectors. The viral systems use transfection of shorthairpin RNA (shRNA)-expressing vectors to produce siRNA in a cell 12.Author: Zhili Yu, Junxiao Ye, Xing Pei, Lu Sun, Ergang Liu, Jianxin Wang, Yongzhuo Huang, Seung Jin Lee, Hui...
https://www.sciencedirect.com/science/article/pii/S0168365916303534
In recent studies, Liposome-Protamine-siRNA (LPR) particles have been demonstrated to represent one of the most effective delivery vehicles for siRNA among the lipid-based carrier systems. LPR particles consist of hyaluronic acid and siRNA that are complexed with the cationic peptide protamine.Author: Venkatesh Rengaswamy, Doris Zimmer, Regine Süss, Jochen Rössler
https://pubs.acs.org/doi/pdf/10.1021/mp500426r
protamine, and cell penetrating peptides (CPP), as well as peptide targeting ligands that have been extensively used in RNA delivery. The delivery strategies, applications, and limitations of these cationic peptides in siRNA/miRNA delivery will be discussed.Author: Ravi S. Shukla, Bin Qin, Kun Cheng
https://www.cell.com/molecular-therapy-family/molecular-therapy/pdf/S1525-0016(16)32258-4.pdf
(RNAi) therapy to target CD47 by systemically delivering siRNA formulated in the liposome-protamine-hyaluronic acid (LPH) nanoparticles (NPs). The LPH-NP is a well-established in vivo siRNA delivery system that is optimized for systemic delivery of siRNA to …File Size: 2MB
https://www.hindawi.com/journals/jdd/2017/6971297/
Over the past 20 years, a diverse group of ligands targeting surface biomarkers or receptors has been identified with several investigated to target siRNA to tumors. Many approaches to developing tumor-homing peptides, RNA and DNA aptamers, and single-chain variable fragment antibodies by using phage display, in vitro evolution, and recombinant antibody methods could not have been imagined by ...Author: Qixin Leng, Martin C. Woodle, A. James Mixson
https://pubs.acs.org/doi/10.1021/acsami.6b09991
Here, we report the construction of a novel siRNA delivery system, sTOLP, which is based on cell penetrating peptide oleoyl-octaarginine (OA-R8) modified multifunctional lipid nanoparticles. sTOLP nanoparticles are composed of a protamine complexed siRNA core, OA-R8, cationic and PEGylated lipids, and transferrin as a targeting ligand. sTOLP formulation was optimized and characterized in …Author: Yuhuan Li, Robert J. Lee, Robert J. Lee, Kongtong Yu, Ye Bi, Yuhang Qi, Yating Sun, Yujing Li, Jing ...
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