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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218546/
Given supportive statements by the ACOG, 58 the recent FDA approval handed down on February 3, 2011, 1 and the absence of proven alternatives, the use of progesterone supplementation to reduce the risk of recurrent preterm birth in women at high risk can no longer be regarded as investigational.Author: Errol R Norwitz, Aaron B Caughey
https://www.nichd.nih.gov/newsroom/releases/040611-progesterone-and-preterm-birth
Progesterone treatment was associated with a lower rate of preterm delivery at less than 33 weeks (8.9 percent in the progesterone group versus 16.1 percent in the placebo group). Differences in the rate of preterm birth were also seen in births before 28 and 35 weeks of pregnancy.
https://www.webmd.com/baby/news/20110406/progesterone-gel-reduces-risk-of-early-preterm-birth
Apr 06, 2011 · April 6, 2011 -- Progesterone gel may reduce the chances of early preterm birth in some women who are considered high risk, according to new research in …
https://www.bmj.com/content/355/bmj.i5206
Oct 05, 2016 · What you need to know. The best intervention for prevention of spontaneous preterm birth in women with risk factors is still unclear. In women with a singleton pregnancy risk of preterm birth and with a short cervix, the evidence for use of cervical cerclage is …Author: Sarah J Stock, Khaled M K Ismail
http://www.uptodate.com/contents/progesterone-supplementation-to-reduce-the-risk-of-spontaneous-preterm-birth
Fonseca EB, Celik E, Parra M, et al. Progesterone and the risk of preterm birth among women with a short cervix. N Engl J Med 2007; 357:462. Hassan SS, Romero R, Vidyadhari D, et al. Vaginal progesterone reduces the rate of preterm birth in women with a sonographic short cervix: a multicenter, randomized, double-blind, placebo-controlled trial.
https://www.medscape.org/viewarticle/457097
Oct 03, 2019 · June 11, 2003 -- Progesterone reduces the risk of recurrent preterm delivery in high-risk women, according to the results of a multicenter, double-blind, placebo-controlled trial published in the June 12 issue of the New England Journal of Medicine.
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