We have collected information about Prodrugs As Novel Drug Delivery Systems for you. Follow the links to find out details on Prodrugs As Novel Drug Delivery Systems.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751454/
Feb 05, 2008 · Central nervous system (CNS) drug delivery remains a major challenge, despite extensive efforts that have been made to develop novel strategies to overcome obstacles. Prodrugs are bioreversible derivatives of drug molecules that must undergo an enzymatic and/or chemical transformation in vivo to release the active parent drug, which subsequently exerts the desired …Author: Jarkko Rautio, Krista Laine, Mikko Gynther, Jouko Savolainen
http://pubs.acs.org/isbn/9780841202917
ACS Journals ; ACS eBooks ; C&EN Global Enterprise; A; Accounts of Chemical Research; ACS Applied Bio Materials
https://www.sciencedirect.com/topics/medicine-and-dentistry/prodrug
Prodrug is a common approach for achieving tissue-specific drug delivery and reducing toxic side effects. As a case in point, tumor microenvironment (TME), which is characterized by acidic pH, elevated temperature, and overexpressed proteases, provide a useful target for triggering the activation of …
https://www.researchgate.net/publication/236006801_Prodrug_Approach_to_Better_Drug_Delivery
In both drug discovery and drug development, prodrugs have become an established tool for improving physicochemical, biopharmaceutical or pharmacokinetic properties of pharmacologically active agents that overcome barriers to a drug's usefulness. To illustrate the applicability of the prodrug strategy…
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/prodrugs
Prodrugs are a class of drug delivery systems in which the drug is covalently conjugated to hydrophilic small molecules or polymers.
https://www.researchgate.net/publication/318293455_THE_NOVEL_DRUG_DELIVERY_SYSTEM
Oral controlled drug delivery forms a crucial facet among novel drug delivery systems. Rational approach to enhance bioavailability and improve pharmacokinetic and pharmacodynamic profile of ...
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