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https://www.sciencedirect.com/science/article/pii/S0002937816002842
Preterm birth (PTB), defined as delivery before 37 weeks of gestation, affects 15 million infants born each year, varying from approximately 5% to 18% of all births across different geographies worldwide. 1 In the United States, it is the leading cause of neonatal death and the second-leading cause of death in children before age 5 years. PTB is also a major source of long-term health ...Author: George R. Saade, Kim A. Boggess, Scott A. Sullivan, Glenn R. Markenson, Glenn R. Markenson, Jay D. I...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033518/
Spontaneous preterm birth remains the leading cause of neonatal morbidity and mortality worldwide, and accounts for a significant global health burden. Several obstetric strategies to screen for spontaneous preterm delivery, such as cervical length and fetal fibronectin measurement, have emerged.Author: Moeun Son, Emily S. Miller
https://www.ncbi.nlm.nih.gov/pubmed/30309793
In preterm premature rupture of membranes (PPROM), CL is devoid of infectious risk and predicts duration of the latency phase but not the risk of perinatal sepsis. Asymptomatic women at risk should be screened at a 2-week interval starting from 16 to 18 weeks, up to 24 weeks. ... Stable CL calls for term delivery. Funneling does not improve ...Author: Yves Ville, Patrick Rozenberg
https://www.hindawi.com/journals/jp/2018/8367571/
T. Nikolova, O. Bayev, N. Nikolova, and G. C. Di Renzo, “Comparison of a novel test for placental alpha microglobulin-1 with fetal fibronectin and cervical length measurement for the prediction of imminent spontaneous preterm delivery in patients with threatened preterm labor,” Journal of Perinatal Medicine, vol. 43, no. 4, pp. 395–402, 2015.Author: Zeynep Asli Oskovi Kaplan, A. Seval Ozgu-Erdinc
https://www.sciencedirect.com/science/article/pii/S1744165X18301112
Quantitative fFN has largely superseded the qualitative test as a predictor of imminent delivery, allowing clinicians to use different thresholds to define risk. A prospective cohort study of 300 women in threatened preterm labour showed that fFN concentration correlated with risk of preterm delivery . For fFN levels <10 ng/mL, there was a ...Author: Natalie Suff, Lisa Story, Andrew Shennan
https://www.seraprognostics.com/category/publications/
The conclusions of the study and resulting American Journal of Obstetrics & Gynecology was that a serum-based molecular predictor identifies asymptomatic pregnant women at risk of spontaneous preterm delivery, which may provide utility in identifying women at risk at an early stage of pregnancy to allow for clinical intervention. MORE >
https://www.nejm.org/doi/full/10.1056/NEJM199602293340904
The clinical value of funneling as a predictor of preterm delivery was similar to that of the cervical length , but the data on funneling are confounded by substantial variation among centers ...Author: Jay D. Iams, Robert L. Goldenberg, Paul J. Meis, Brian M. Mercer, Atef Moawad, Anita Das, Elizabeth ...
https://www.uptodate.com/contents/preterm-labor-clinical-findings-diagnostic-evaluation-and-initial-treatment
(See "Preterm birth: Risk factors, interventions for risk reduction, and maternal prognosis" and "Inhibition of acute preterm labor".) PATHOGENESIS OF PRETERM LABOR. The pathophysiology of preterm labor involves at least four primary pathogenic processes that result in a final common pathway ending in spontaneous preterm labor and delivery:
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