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https://pubs.acs.org/doi/abs/10.1021/bm301166s
Polyplex formation between the qNG and nucleic acid exemplified by plasmid DNA (pDNA) and short interfering RNA (siRNA duplexes) were evaluated. The delivery of polyplexes was optimized for the delivery of pDNA and siRNA to the Drosophila Schneider 2 (S2) cell-line.Author: Saadyah E. Averick, Eduardo Paredes, Ainara Irastorza, Arun R. Shrivats, Abiraman Srinivasan, Daniel...
https://pubs.acs.org/doi/10.1021/bm301166s
Cationic nanogels with site-selected functionality were designed for the delivery of nucleic acid payloads targeting numerous therapeutic applications. Functional cationic nanogels containing quaternized 2-(dimethylamino)ethyl methacrylate and a cross-linker with reducible disulfide moieties (qNG) were prepared by activators generated by electron transfer (AGET) atom transfer radical ...Author: Saadyah E. Averick, Eduardo Paredes, Ainara Irastorza, Arun R. Shrivats, Abiraman Srinivasan, Daniel...
https://www.ncbi.nlm.nih.gov/pubmed/22967138
Nov 12, 2012 · Polyplex formation between the qNG and nucleic acid exemplified by plasmid DNA (pDNA) and short interfering RNA (siRNA duplexes) were evaluated. The delivery of polyplexes was optimized for the delivery of pDNA and siRNA to the Drosophila Schneider 2 (S2) cell-line.Author: Saadyah E. Averick, Eduardo Paredes, Ainara Irastorza, Arun R. Shrivats, Abiraman Srinivasan, Daniel...
https://pubs.acs.org/doi/suppl/10.1021/bm301166s/suppl_file/bm301166s_si_001.pdf
1 Supporting Information: Preparation of Cationic Nanogels for Nucleic Acid Delivery Saadyah E. Averick,a Eduardo Paredes,a’ Arun R. Shrivats, b Ainara Irastorza,b Abiraman Srinivasan, a Daniel J. Siegwart,a Andrew J. Magenau, a Hong Y. Cho, a Eric Hsu, bAmram Averick,a Jinku Kim, b Shiguang Liu, b Jeffrey O. Hollinger, b Subha Das a’ and Krzysztof Matyjaszewski *a
http://www.arunrshrivats.com/files/2012_Averick_Biomacromolecules.pdf
32,33 and NGs for delivery of small molecules34 and 47 carbohydrates. 35 However, in order to use these materials for 48 effective nucleic acid delivery, it is necessary to have site-specific 49 incorporation of cationic monomers, into the predominant 50 OEOMA NGs for polyplex formation, but currently this has not been accomplished. ATRP 51
https://www.researchgate.net/publication/230831621_Preparation_of_Cationic_Nanogels_for_Nucleic_Acid_Delivery
Another approach to utilize cationic molecules for delivery of nucleic acid payloads to cells is the preparation of star mac- romolecules capable of direct conjugation with DNA. Star copolymers...
https://www.sigmaaldrich.com/catalog/papers/22967138
Abstract Cationic nanogels with site-selected functionality were designed for the delivery of nucleic acid payloads targeting numerous therapeutic applications. Functional cationic nanogels containing quaternized 2-(dimethylamino)ethyl methacrylate and a cross-linker with reducible...
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