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https://www.ncbi.nlm.nih.gov/pubmed/12052693
Jun 04, 2002 · Floating beads were prepared from a sodium alginate solution containing CaCO(3) or NaHCO(3) as gas-forming agents. The solution was dropped to 1% CaCl(2) solution containing 10% acetic acid for CO(2) gas and gel formation. The effects of gas-forming agents on bead size and floating properties were investigated.Author: B. Y. Choi, Hyun Jin Park, S. J. Hwang, J. B. Park
https://www.researchgate.net/publication/10628344_Preparation_of_floating_alginate_gel_beads_for_drug_delivery_to_the_gastric_mucosa
(9,10) Such beads have also been used in the design of floating systems in order to prolong gastric retention time (11,12) The floating and sustained drug release properties of calcium alginate ...
https://www.academia.edu/2344742/Preparation_of_alginate_beads_for_floating_drug_delivery_system_effects_of_CO_sub_2_sub_gas-forming_agents
Preparation of alginate beads for floating drug delivery system: effects of CO< sub> 2 gas-forming agents
https://www.sciencedirect.com/science/article/pii/S0939641100001107
Calcium-induced alginate gel beads (Alg–Ca) have been developed in recent years as a unique vehicle for drug delivery. Alg–Ca is rapidly formed by gelation of alginic acid in the presence of calcium ions and is able to incorporate some compounds such as drugs …Author: Y Murata, N Sasaki, E Miyamoto, S Kawashima
https://www.sciencedirect.com/science/article/abs/pii/S0939641100001107
Use of floating alginate gel beads for stomach-specific drug delivery. Abstract. Two types of alginate gel beads capable of floating in the gastric cavity were prepared. The first, alginate gel bead containing vegetable oil (ALGO), is a hydrogel bead and its buoyancy is attributable to vegetable oil held in the alginate gel matrix.Author: Y Murata, N Sasaki, E Miyamoto, S Kawashima
http://www.imedpub.com/articles/formulation-development-and-characterization-of-alginate-beads-of-ranitidine-hydrochloride.pdf
Preparation of floating alginate beads is more suitable because it is a multiparticulate system, utilizes cheap and nontoxic polymers and there is no use of any organic solvent. TheseAuthor: Navneet Kumar Verma, Shivendra Pratap Singh, Praveen Kumar Rai, Reena Singh, Ashok Kumar Tripathi
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178975/
The results suggested that cod liver oil entrapped calcium alginate beads were promising as a carrier for intragastric floating drug delivery of famotidine.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750381/
Oct 19, 2005 · The purpose of writing this review on floating drug delivery systems (FDDS) was to compile the recent literature with special focus on the principal mechanism of floatation to achieve gastric retention. The recent developments of FDDS including the physiological ...Author: Shweta Arora, Javed Ali, Alka Ahuja, Roop K. Khar, Sanjula Baboota
https://www.mdpi.com/1420-3049/16/12/10347/pdf
floating beads were prepared by suspending octodecanol and berberine in sodium alginate (SA) solution. The suspension was then dripped into a solution of calcium chloride.Author: Zhen-Hai Zhang, Yong-Shun Sun, Hui Pang, Were L.L. Munyendo, Hui-Xia Lv, Sheng-Liang Zhu
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