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https://www.sciencedirect.com/science/article/pii/S0079670007000500
In recent years, the development of stimuli-sensitive systems (i.e., intelligent or smart systems) for protein delivery has been a subject of significant pharmaceutical importance, as the systems can recognize environmental changes, induce structural changes, and release therapeutic proteins in a …Author: Kuen Yong Lee, Soon Hong Yuk
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
The aim of this section is to review recent developments in temperature and pH-responsive polymers and highlight the emerging area of redox-responsive polymers for drug delivery systems. Additionally, a brief introduction to magnetically-triggered polymer nanocomposites is given below.Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
https://www.researchgate.net/publication/223271246_Polymeric_protein_delivery_systems
Several biodegradable materials have been investigated in the development of protein delivery systems, such as matrix, micro-structural, or nano-structural forms [8]. For intracellular protein ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471357/
Mar 15, 2019 · Similar polymeric co-delivery systems were also used that enclosed the hydrophobic irinotecan (CPT) and hydrophilic DOX HCl, which inhibited the activity of topoisomerase I and II and exhibited an enhanced therapeutic effect on breast and brain tumors .Author: Jiayi Pan, Kobra Rostamizadeh, Nina Filipczak, Vladimir P. Torchilin
https://www.researchgate.net/publication/317354436_Updates_on_smart_polymeric_carrier_systems_for_protein_delivery
Updates on smart polymeric carrier systems for protein delivery Article (PDF Available) in Drug Development and Industrial Pharmacy 43(10):1-42 · June 2017 with 728 Reads How we measure 'reads'
https://www.sciencedirect.com/science/article/pii/S1319016414000590
Protein and peptide degradation is highest in the stomach and duodenum and is significantly decreased in the ileum and colon. Various delivery systems have been developed to target absorption from the colon and ileum as a result, and minimize exposure of drug to proteolytic enzymes.Author: Abdul Muheem, Faiyaz Shakeel, Mohammad Asadullah Jahangir, Mohammed Anwar, Neha Mallick, Gaurav Kuma...
https://www.slideshare.net/YaminiShah/protein-and-peptide-delivery-system
Mar 22, 2016 · Protein and peptide delivery system 1. 1 2. More than 7000 naturally occurring peptides • Hormones, • Neurotransmitters, • Growth factors, • Ion channel ligands peptides are selective and efficacious signaling molecules that bind to specific cell surface receptors • Ex. G protein-coupled receptors (GPCRs) or ion channels, where they trigger intracellular effects. peptides represent ...
https://pubs.acs.org/doi/10.1021/acsnano.9b10015
Polymeric nanoparticles (NPs) are an important category of drug delivery systems, and their in vivo fate is closely associated with delivery efficacy. Analysis of the protein corona on the surface of NPs to understand the in vivo fate of different NPs has been shown to be reliable but complicated and time-consuming. In this work, we establish a simple approach for predicting the in vivo fate ...Author: Zhi-Ting Cao, Li-Qin Gan, Wei Jiang, Ji-Long Wang, Hou-Bing Zhang, Yue Zhang, Yucai Wang, Xianzhu Ya...
https://www.thefreelibrary.com/Polymeric+delivery+systems+in+biotechnology%3a+a+mini+review.-a0169211139
Jul 01, 2007 · Polymeric delivery systems in biotechnology: a mini review. Link/Page Citation ... Multiple pulsed delivery of gene or protein from resorbable polymeric microchip devices and microencapsulation technologies that employ immunoisolating devices surrounded by microfabricated nanoporous membranes are some other innovations in the area of controlled ...
https://www.mdpi.com/1420-3049/21/8/1002/htm
Stimuli-responsive polymeric delivery systems have a potential to at most overcome the challenges faced with ocular protein and peptide delivery. A group of stimuli-responsive drug delivery systems known as in situ forming systems has increasingly gained interest over the years.Author: Pakama Mahlumba, Yahya E. Choonara, Pradeep Kumar, Lisa C. Du Toit, Viness Pillay
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