Polymeric Materials For Gene Delivery And Dna Vaccination

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Polymeric Materials for Gene Delivery and DNA Vaccination

    https://www.researchgate.net/publication/228008803_Polymeric_Materials_for_Gene_Delivery_and_DNA_Vaccination
    In particular, we highlight work on new polymeric materials and their effects on protective immune activation, gene delivery, and current efforts to optimize polymeric delivery systems for DNA ...

Polymeric Materials for Gene Delivery and DNA Vaccination ...

    http://onlinelibrary.wiley.com/doi/10.1002/adma.200801478/abstract
    This Review focuses on the recent progress and challenges facing materials design for nonviral DNA vaccine drug delivery systems. In particular, we highlight work on new polymeric materials and their effects on protective immune activation, gene delivery, and current efforts to optimize polymeric delivery systems for DNA vaccination.

Polymeric Materials for Gene Delivery and DNA Vaccination.

    https://www.ncbi.nlm.nih.gov/pubmed/28413262
    Feb 23, 2009 · This Review focuses on the recent progress and challenges facing materials design for nonviral DNA vaccine drug delivery systems. In particular, we highlight work on new polymeric materials and their effects on protective immune activation, gene delivery, and current efforts to optimize polymeric delivery systems for DNA vaccination.Author: David N. Nguyen, Jordan J. Green, Juliana M. Chan, Robert Langer, Daniel G. Anderson

Polymeric Materials for Gene Delivery and DNA Vaccination ...

    http://europepmc.org/articles/PMC5391878
    Feb 01, 2009 · Gene delivery holds great potential for the treatment of many different diseases. Vaccination with DNA holds particular promise, and may provide a solution to many technical challenges that hinder traditional vaccine systems including rapid development and production and induction of robust cell-mediated immune responses.Author: David N. Nguyen, Jordan J. Green, Juliana M. Chan, Robert Langer, Daniel G. Anderson

Polymeric Materials for Gene Delivery and DNA Vaccination

    http://www.julianachan.org/PDF/04-NguyenDN.pdf
    Polymeric Materials for Gene Delivery and DNA Vaccination By David N. Nguyen, Jordan J. Green, Juliana M. Chan, Robert Langer, and Daniel G. Anderson* 1. Introduction The principles of vaccination pioneered by Jenner and others in the early 19th century remain relatively unchanged in clinical practice. Despite almost two centuries of use and ...

DNA Vaccines—How Far From Clinical Use?

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274812/
    Nov 15, 2018 · More recently, the DNA vaccine delivery properties of orally applied bacteria, for example with regard to phagolysosomal escape have been improved by additional coating with NC . Compared with other sytemic routes of DNA vaccination, pulmonary application of aerolized DNA vaccines is a rather new approach .Author: Dominika Hobernik, Matthias Bros

Polymeric Materials for Gene Delivery and DNA Vaccination ...

    https://www.deepdyve.com/lp/wiley/polymeric-materials-for-gene-delivery-and-dna-vaccination-ZopsXTY4FI
    Feb 23, 2009 · Read "Polymeric Materials for Gene Delivery and DNA Vaccination, Advanced Materials" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

Polymer multilayer tattooing for enhanced DNA vaccination ...

    https://www.nature.com/articles/nmat3550
    Jan 27, 2013 · Microneedle arrays coated with a pH-sensitive releasable layer act as an intradermal delivery system for polyelectrolyte films containing bioactive molecules for …Author: Peter C. DeMuth, Younjin Min, Bonnie Huang, Joshua A. Kramer, Andrew D. Miller, Dan H. Barouch, Dan ...

Polymer systems for gene delivery—Past, present, and ...

    https://www.sciencedirect.com/science/article/pii/S0079670007000718
    Although these safety issues do not necessarily preclude the use of viruses as gene vectors, they have motivated the exploration for safer, less pathogenic and immunogenic gene delivery alternatives including lipid-based vectors, chemically modified viruses, inorganic materials, and …Author: Sharon Y. Wong, Jeisa M. Pelet, David Putnam

Polymeric nanoparticle‐based delivery of TRAIL DNA for ...

    https://aiche.onlinelibrary.wiley.com/doi/10.1002/btm2.10019
    We also investigated to what extent the non‐viral delivery of DNA encoding the TRAIL gene could cause cell death in various cancer cell lines. Finally, we examined mechanisms of resistance in cancer cells lines that were less responsive to TRAIL treatment. 2 Materials and methods 2.1 Polymer synthesisAuthor: Stephany Y. Tzeng, David R. Wilson, Sarah K. Hansen, Alfredo Quiñones-Hinojosa, Jordan J. Green

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