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http://microspheres.us/drug_delivery/motivations-biodegradable-microspheres-drug-delivery/187.html
Polymer microspheres delivery systems offer a lot of advantages in chemotherapy where they provided localized sustained release and reduced toxicity at the same time, since the drug can be localized by direct injection of drug-loaded-microspheres into tumor tissue, thus minimizing negative effect to …
https://www.jgtps.com/admin/uploads/YqxI0h.pdf
Microspheres received much attention not only for prolonged release, but also for targeting of drugs. In future microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, genetic materials, targeted and effective drug delivery. The current aim of …
https://www.sciencedirect.com/science/article/pii/S0378517304002492
Today new methods of drug delivery are possible: desired drug release can be provided by rate-controlling membranes or by implanted biodegradable polymers containing dispersed medication. Over the past 25 years much research has also been focused on …Author: S. Freiberg, X.X. Zhu
https://www.researchgate.net/publication/251572443_Microsphere_as_a_novel_drug_delivery
Microsphere as a novel drug delivery. ... by the molecular structure of the drug and the polymer, the resistance of the polymer to degradation, and the surface area along with the porosity of the ...
https://www.polymicrospheres.com/
PolyMicrospheres, founded in 1990, specializes in microparticle development and controlled-release technologies. Using the most innovative polymerization and microencapsulation techniques, we develop and manufacture a complete range of microspheres and drug delivery systems.
https://www.ncbi.nlm.nih.gov/pubmed/14680467
Microspheres for controlled release drug delivery. ... Polymeric microspheres are ideal vehicles for many controlled delivery applications due to their ability to encapsulate a variety of drugs, biocompatibility, high bioavailability and sustained drug release characteristics. ... Furthermore, recent advances in the use of polymer microsphere ...Author: Neelesh K Varde, Daniel W Pack
https://link.springer.com/chapter/10.1007%2F978-0-387-25842-3_2
Thus, there is a corresponding need for safer and more effective methods and devices for drug delivery. Indeed, drug delivery systems—designed to provide a therapeutic agent in the needed amount, at the right time, to the proper location in the body, in a manner that optimizes efficacy, increases compliance and minimizes side effects—were ...Author: Kyekyoon Kevin Kim, Daniel W. Pack
https://www.sciencedirect.com/science/article/pii/S0141813019364980
The rate and extent of drug release, for instance, are controlled by drug and polymer characteristic, particle sizes and size distribution of microspheres, drug-polymer ratio and release medium. Additionally, cross-linking has also been shown to prolong drug lifetime in the body.Author: Nguyen Thi Thanh Uyen, Zuratul Ain Abdul Hamid, Nguyen Xuan Thanh Tram, Nurazreena Ahmad
http://ijpsr.com/bft-article/microspheres-as-drug-carriers-for-controlled-drug-delivery-a-review/?view=fulltext
ABSTRACT: Microspheres play a very important role as particulate drug delivery system because of their small size and other efficient properties. Microspheres have been proved to be a suitable bridge to scale the distance over to formulate an effective dosage form, to simulate controlled drug release.
https://www.researchgate.net/publication/225704244_Degradable_Polymer_Microspheres_for_Controlled_Drug_Delivery
Controlled drug delivery technology is concerned with the systematic release of a pharmaceutical agent to maintain a therapeutic level of the drug in the body for a sustained period of time.
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