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https://www.sciencedirect.com/science/article/pii/S0022354916325539
Intratumoral, drug‐releasing implants are a subset of the intratumoral drug delivery paradigm and have shown increasing promise in recent years. Driven by developments for the treatment of prostate 50, 51 and brain cancers, 52, 53 implantable devices containing either radioactive elements or chemotherapeutic drugs have become viable treatment ...Author: Brent D. Weinberg, Elvin Blanco, Jinming Gao
https://www.researchgate.net/publication/5993611_Polymer_Implants_for_Intratumoral_Drug_Delivery_and_Cancer_Therapy
Polymer Implants for Intratumoral Drug Delivery and Cancer Therapy Article · Literature Review in Journal of Pharmaceutical Sciences 97(5):1681-702 · May 2008 with 202 Reads How we measure 'reads'
http://www4.utsouthwestern.edu/gaolab/Pictures/Publication%20pdfs/61_Weinberg_JPS.pdf
Polymer Implants for Intratumoral Drug Delivery and Cancer Therapy BRENT D. WEINBERG,1 ELVIN BLANCO, 2JINMING GAO 1Department of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Ave, Cleveland, Ohio 44106 2Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd., Dallas, Texas 75390
https://onlinelibrary.wiley.com/doi/full/10.1002/jps.21038
To address the need for minimally invasive treatment of unresectable tumors, intratumoral polymer implants have been developed to release a variety of chemotherapeutic agents for the locoregional therapy of cancer. These implants, also termed “polymer millirods,” were designed to provide optimal drug release kinetics to improve drug ...Author: Brent D. Weinberg, Elvin Blanco, Jinming Gao
https://www.sciencedirect.com/science/article/abs/pii/S0022354916325539
Polymer Implants for Intratumoral Drug Delivery and Cancer Therapy. ... intratumoral polymer implants have been developed to release a variety of chemotherapeutic agents for the locoregional therapy of cancer. These implants, also termed “polymer millirods,” were designed to provide optimal drug release kinetics to improve drug delivery ...Author: Brent D. Weinberg, Elvin Blanco, Jinming Gao
https://utsouthwestern.pure.elsevier.com/en/publications/polymer-implants-for-intratumoral-drug-delivery-and-cancer-therap
title = "Polymer implants for intratumoral drug delivery and cancer therapy", abstract = "To address the need for minimally invasive treatment of unresectable tumors, intratumoral polymer implants have been developed to release a variety of chemotherapeutic agents for the locoregional therapy of cancer.Author: Brent D. Weinberg, Elvin Blanco, Jinming Gao
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845536/
Jan 01, 2009 · Polymer millirods for the intratumoral delivery of β-lap to prostate tumors were produced as described in ‘Materials and Methods’, and release kinetics of the drug in vitro were examined. Since a 2 h exposure of β-lap resulted in irreversible cell death, an initial burst of the drug was desired to rapidly achieve therapeutic levels.Author: Ying Dong, Shook Fong Chin, Elvin Blanco, Erik A. Bey, Wareef Kabbani, Xian Jin Xie, William G. Born...
https://scholars.houstonmethodist.org/en/publications/polymer-implants-for-intratumoral-drug-delivery-and-cancer-therapy(20422e3a-a8e8-4226-8038-6a85be56f6be).html
To address the need for minimally invasive treatment of unresectable tumors, intratumoral polymer implants have been developed to release a variety of chemotherapeutic agents for the locoregional therapy of cancer. These implants, also termed "polymer millirods," were designed to provide optimal drug release kinetics to improve drug delivery ...Author: Brent D. Weinberg, Elvin Blanco, Jinming Gao
https://clincancerres.aacrjournals.org/content/15/1/131
Jan 01, 2009 · Purpose: β-Lapachone (ARQ 501, a formulation of β-lapachone complexed with hydroxypropyl-β-cyclodextrin) is a novel anticancer agent with selectivity against prostate cancer cells overexpressing the NAD(P)H:quinone oxidoreductase-1 enzyme. Lack of solubility and an efficient drug delivery strategy limits this compound in clinical applications.Author: Ying Dong, Shook Fong Chin, Elvin Blanco, Erik A. Bey, Wareef Kabbani, Xian Jin Xie, William G. Born...
https://clincancerres.aacrjournals.org/content/clincanres/15/1/131.full.pdf
Intratumoral Delivery of B-Lapachone via Polymer Implants for Prostate Cancer Therapy ... (h-lapachone)while enabling drug delivery technology (poly-mer millirods)to achieve tumor- and site-specific therapy of human prostate cancers. Materials and Methods Materials.Author: Ying Dong, Shook Fong Chin, Elvin Blanco, Erik A. Bey, Wareef Kabbani, Xian Jin Xie, William G. Born...
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