We have collected information about Poly-L-Lysine Gene Delivery for you. Follow the links to find out details on Poly-L-Lysine Gene Delivery.
https://biomaterialsres.biomedcentral.com/articles/10.1186/s40824-019-0156-z
Mar 12, 2019 · Gene delivery systems based on poly(L-lysine) Poly(L-lysine)(PLL) is one of the cationic polymers for gene transfers. PLL is a homo-polypeptide belonging to the group of cationic polymers at pH 7. PLL contains a positively charged hydrophilic amino group.Author: YK Sung, SW Kim
https://www.ncbi.nlm.nih.gov/pubmed/24813391
We developed novel gene vectors composed of dendrigraft poly-L-lysine (DGL). The transgene expression efficiency of the pDNA/DGL complexes (DGL complexes) was markedly higher than that of the control pDNA/poly-L-lysine complex. However, the DGL complexes caused cytotoxicity and erythrocyte agglutination at high doses.Author: Yukinobu Kodama, Tadahiro Nakamura, Tomoaki Kurosaki, Kanoko Egashira, Toyoharu Mine, Hiroo Nakagawa...
https://www.sciencedirect.com/topics/neuroscience/polylysine
Dayananda Kasala, Chae-Ok Yun, in Adenoviral Vectors for Gene Therapy (Second Edition), 2016. 2.2 Poly(l-lysine)-Coated AdPoly(l-lysine) is a linear polypeptide bearing free amine side arms that is able to interact with negatively charged nucleic acids or Ad, leading to the formation of a complex with a high net positive charge via electrostatic interaction.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832905/
Oct 17, 2019 · The ternary complex formed with DNA showed high transfection efficiency in the liver, lungs and spleen of experimental animals. Other investigators are synthesizing copolymers of poly-L-lysine for enhanced gene delivery applications . Several other cationic peptides have also found use as biocompatible and biodegradable gene delivery vehicles.Author: T. J. Thomas, Heidar-Ali Tajmir-Riahi, C. K. S. Pillai
https://www.sciencedirect.com/science/article/pii/S0168365901002735
May 14, 2001 · Anti-JL1 antibody-conjugated poly (l-lysine) for targeted gene delivery to leukemia T ... We have designed the gene delivery carrier targeted to Molt 4 cells, human leukemia T cells, using monoclonal antibody against leukemia-specific JL1 antigen, anti-JL1 antibody, as a targeting moiety. ... at carbohydrate sites and conjugated to thiolated ...Author: Wonhee Suh, June Key Chung, Seong Hoe Park, Sung Wan Kim
https://en.wikipedia.org/wiki/Polylysine
While the poly-L-lysine (PLL) precursor amino acid occurs naturally, the poly-D-lysine (PDL) precursor is an artificial product. The latter is therefore thought to be resistant to enzymatic degradation and so may prolong cell adherence. Polylysine in drug deliveryChemical formula: (C₆H₁₂N₂O)ₙ
https://link.springer.com/protocol/10.1385%2F1-59259-141-8%3A001
Abstract. Nonviral gene delivery has great potential for replacement of recombinant protein therapy. In many cases, gene therapies would be a considerable improvement over existing therapies because of putative advantages in dosing schedule, patient compliance, toxicity, immunogenicity, and cost.Author: Charles P. Lollo, Mariusz G. Banaszczyk, Patricia M. Mullen, Christopher C. Coffin, Dongpei Wu, Alis...
Searching for Poly-L-Lysine Gene Delivery?
You can just click the links above. The data is collected for you.
