Pluronic Drug Delivery

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Pluronic Block Copolymers: Evolution of Drug Delivery ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678942/
    Sep 10, 2008 · A series of studies used Pluronic P105 micelles for the delivery of Dox into solid tumors in mice [ 38 - 41 ]. In these studies the localized ultrasonic irradiation of the tumor was applied upon accumulation of the micelles in the tumor interstitium to facilitate the drug release into the tumor cells [ …Author: Elena V. Batrakova, Alexander V. Kabanov, Alexander V. Kabanov

Recent progress in drug delivery of pluronic P123 ...

    https://www.ncbi.nlm.nih.gov/pubmed/28135859
    This review focuses on recent investigations that used Pluronic P123 (P123) as pharmaceutical ingredients in vesicle, micelle, mixed micelle, in situ gel, tablet and emulsion. The main results from these studies show that P123 can significantly increase the stability of incorporated hydrophobic drugs with enhanced in vitro cytotoxicity and cellular uptake of anticancer drugs.Author: Li-Yan Zhao, Wan-Ming Zhang

Pluronic lecithin organogel as a topical drug delivery system.

    https://www.ncbi.nlm.nih.gov/pubmed/22747074
    Pluronic lecithin organogel as a topical drug delivery system. Pandey M(1), Belgamwar V, Gattani S, Surana S, Tekade A. Author information: (1)Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra, India.Author: Mohit Pandey, Veena Belgamwar, Surendra Gattani, Sanjay Surana, Avinash Tekade

Pluronic block copolymers: Evolution of drug delivery ...

    https://www.sciencedirect.com/science/article/pii/S0168365908002216
    Pluronic micelles for drug delivery Incorporation of low molecular mass drugs into Pluronic micelles can increase drug solubility and drug stability, and can improve drug …Author: Elena V. Batrakova, Alexander V. Kabanov, Alexander V. Kabanov

Stabilization and Release Effects of Pluronic F127 in ...

    https://www.hcs.harvard.edu/~jus/england.pdf
    mechanism for a polypeptide solute. Thus, Pluronic F127 was affirmed as a powerful mechanism for protein drug delivery, and more insight was gleaned into the mechanisms of its operation. Jeremy L. England is currently a high school senior at Phillips Exeter Academy. He hopes to pursue a career in either physics or biomedical research.

Stabilization and activation of Pluronic micelles for ...

    https://www.sciencedirect.com/science/article/pii/S0927776599000636
    Kabanov et al. , concluded that the efficacy of Pluronic delivery systems was based on the presence of Pluronic unimers. The drop in the efficacy of drug/Pluronic systems above the CMC may result from the recently reported substantial decrease in the intracellular drug uptake from dense Pluronic micelles , , . The drug incorporated into the micelle core is masked from the external media by the corona …Author: Natalya Rapoport

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