We have collected information about Pluronic Block Copolymers Drug Delivery for you. Follow the links to find out details on Pluronic Block Copolymers Drug Delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678942/
Sep 10, 2008 · Inhibition of drug efflux transporters by Pluronic block copolymers enhanced transport of wide range of therapeutic agents across polarized brain microvessel endothelial cells and intestinal barrier cells in vitro [ 75] and in vivo [ 47 ]. Thus, brain delivery of a Pgp substrate, digoxin,...Author: Elena V. Batrakova, Alexander V. Kabanov, Alexander V. Kabanov
https://www.sciencedirect.com/science/article/pii/S0168365908002216
Pluronic block copolymers were recently shown to prevent the development of MDR in the cancer cells exposed to the drug [83]. Specifically, sensitive MCF7 cells cultured in the presence of Pluronic P85 were unable to stably grow in concentrations of Dox that exceeded 10 ng Dox/ml in the culture media.Author: Elena V. Batrakova, Alexander V. Kabanov, Alexander V. Kabanov
https://www.sciencedirect.com/science/article/abs/pii/S0168365902000093
Pluronic ® block copolymers are found to be an efficient drug delivery system with multiple effects. The incorporation of drugs into the core of the micelles formed by Pluronic ® results in increased solubility, metabolic stability and circulation time for the drug.Author: Alexander V Kabanov, Elena V Batrakova, Valery Yu Alakhov
http://www.dl.begellhouse.com/journals/3667c4ae6e8fd136,0f44558e592e3fbc,2da9cb966589e4cb.html
Pluronicв block copolymers are recognized pharmaceutical excipients listed in the US and British Pharmacopoeia. The incorporation of drugs into Pluronic micelles results in increased solubility and stability of drugs. Consequently, the micelles are used for delivery of drugs in the body.
https://www.researchgate.net/publication/11326313_Pluronic_Block_Copolymers_in_Drug_Delivery_from_Micellar_Nanocontainers_to_Biological_Response_Modifiers
Pluronic block copolymers are recognized pharmaceutical excipients listed in the US and British Pharmacopoeia. The incorporation of drugs into Pluronic micelles results in increased solubility and stability of drugs. Consequently, the micelles are used for delivery of drugs in the body.
https://www.researchgate.net/publication/5322294_Pluronic_block_copolymers_Evolution_of_drug_delivery_concept_from_inert_nanocarriers_to_biological_response_modifiers
These amphiphilic copolymers are also known by the trade names Pluronic or Poloxamer. Among the wide range of applications of PEO- PPO-PEO copolymers, the most common fields are detergency, foaming, emulsification, lubrication, dispersion stabilization, and drug delivery [1][2][3][4][5][6]. ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122590/
Aug 04, 2014 · One such example is represented by a class of copolymers, called Pluronic block copolymers or poloxamers, that are widely used in various drug delivery systems 21−32 and in tissue engineering. 33−36 Pluronics are triblock copolymers of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO), arranged in PEO-PPO-PEO structure. Depending on the length of the blocks the …Author: Daria Y. Alakhova, Alexander V. Kabanov
http://maroonbiotech.com/pdf/PluronicsforGeneTherapy.pdf
Pluronic block copolymers are recognized pharmaceutical excipients listed in the US and British Pharmacopoeia. They have been used extensively in a variety of pharmaceutical formulations including delivery of low molecular mass drugs and polypeptides. This review describes novel applications of Pluronic block copolymers in gene therapy.
https://www.mdpi.com/2079-4983/9/1/11/pdf
Micelles with various structures (i.e., ellipsoids, rods) are thermodynamically stable. As micelles of different shapes become closely packed, care must be taken to monitor drug release rates. Pluronic P123, for example, can form cylindrical micelles, which stack together, leading to …Author: Andrew M. Bodratti, Paschalis Alexandridis
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