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https://www.sciencedirect.com/science/article/pii/S0378517307008630
The mobility of a drug in PLGA-based delivery systems does not only depend on its own physico-chemical properties and the type of PLGA used, but also to a large extent on the size and shape of the device. In addition, attractive ionic drug-polymer interactions can lead to unexpected low release rates.Author: D. Klose, D. Klose, F. Siepmann, K. Elkharraz, J. Siepmann, J. Siepmann
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347861/
Sep 01, 2011 · In past two decades poly lactic-co-glycolic acid (PLGA) has been among the most attractive polymeric candidates used to fabricate devices for drug delivery and tissue engineering applications.PLGA is biocompatible and biodegradable, exhibits a wide range of erosion times, has tunable mechanical properties and most importantly, is a FDA approved polymer.Author: Hirenkumar K. Makadia, Steven J. Siegel
https://www.ncbi.nlm.nih.gov/pubmed/15719481
PLGA nanoparticles in drug delivery: the state of the art. Bala I(1), Hariharan S, Kumar MN. Author information: (1)Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Punjab, India. Nanoparticles represent drug delivery systems suitable for most administration routes.Author: Indu Bala, Sarita Hariharan, Mnv Ravi Kumar
https://www.researchgate.net/publication/270765946_PLGA_A_unique_polymer_for_drug_delivery
PLGA: A unique polymer for drug delivery. ... A wide range of PLGA-based drug delivery systems have been reported for the treatment or diagnosis of various diseases and disorders. The present ...
https://www.sciencedirect.com/science/article/pii/S0014305719325765
Polymer selection is an important part of the particle design, as polymer properties influence toxicity, pharmacokinetics, and biocompatibility of the drug delivery system . For example, PLGA has attracted considerable attention in the field of drug delivery due to its biocompatibility, injectability, manufacturability, and controlled ...Author: Elina Kibler, Anastasia Lavrinenko, Ilya Kolesnik, Ksenia Stankevich, Ksenia Stankevich, Evgeny Bolb...
http://kinampark.com/PLGARef/files/Xu%202016%2C%20Polymer%20degradation%20and%20drug%20delivery%20in%20PLGA-based%20drug%E2%80%93polymer%20Applications-%20A%20review%20of%20experiments%20and%20theories.pdf
rate and the drug release of a PLGA-based polymer is influ-enced by a number of factors, such as the initial molecular weight (M w), monomer composition ratio of PLGA matrix (i.e., LA/GA ratio), drug type, processing method, and pH value of the release medium.1–14 To fabricate a PLGA-based drug delivery system with higher efficiency and ...
https://www.researchgate.net/publication/266761665_PLGA_Microspheres_Containing_Minocycline_as_Drug_Delivery_System
Also, it has been approved by the Food and Drug Administration (FDA) for drug delivery system. Among different forms of PLGA-based drug delivery systems, microspheres or microparticles are the ...
https://onlinelibrary.wiley.com/doi/abs/10.1111/wrr.12404
It is a well‐established drug delivery system in various medical applications. The aim of the current review is to elaborate the applications of PLGA based drug delivery systems carrying different wound healing agents and also present PLGA itself as a wound healing promoter.Author: Kiran Kumar Chereddy, Gaëlle Vandermeulen, Véronique Préat
https://www.scirp.org/journal/PaperInformation.aspx?PaperID=62762
Jan 01, 2016 · Polymers are being used extensively in drug delivery due to their surface and bulk properties. They are being used in drug formulations and in drug delivery devices. These drug delivery devices may be in the form of implants for controlled drug delivery. Polymers used in colloidal drug carrier systems, consisting of small particles, show great advantage in drug delivery systems because of ...Author: Apurva Srivastava, Tejaswita Yadav, Soumya Sharma, Anjali Nayak, Akanksha Akanksha Kumari, Nidhi Mis...
https://www.nature.com/articles/s41467-019-12141-5
Sep 20, 2019 · Here we report an ultra-long-acting tunable, biodegradable, and removable polymer-based delivery system that offers sustained drug delivery for …Author: S. Rahima Benhabbour, Martina Kovarova, Clinton Jones, Daijha J. Copeland, Roopali Shrivastava, Mich...
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