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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347861/
Sep 01, 2011 · In past two decades poly lactic-co-glycolic acid (PLGA) has been among the most attractive polymeric candidates used to fabricate devices for drug delivery and tissue engineering applications.PLGA is biocompatible and biodegradable, exhibits a wide range of erosion times, has tunable mechanical properties and most importantly, is a FDA approved polymer.Author: Hirenkumar K. Makadia, Steven J. Siegel
https://www.sciencedirect.com/science/article/pii/S0169409X16302113
Polylactic acid (PLA) controlled delivery carriers for biomedical applications ... the rise of commercial formulations for drug delivery, based on either PLGA or PLA matrices, is also expected to increase. This review discusses the current application of engineered PLA particles and the derivatization of these particles with other polymers or ...Author: Betty Mae Tyler, David Gullotti, Antonella Mangraviti, Tadanobu Utsuki, Henry Brem
https://www.sciencedirect.com/science/article/pii/S0169409X12002645
Biodegradation and biocompatibility of PLA and PLGA microspheres ... Numerous articles in the scientific literature of biodegradable microspheres address the significant issue of drug delivery rates from biodegradable microspheres but do not contain significant information relative to biodegradation or biocompatibility issues. ... nanospheres ...Author: James M Anderson, Matthew S Shive
https://www.sigmaaldrich.com/technical-documents/articles/materials-science/plga-drug-delivery.html
Solubility enhancement of hydrophobic drugs via drug-loaded micelles using biodegradable PEG- polyester diblock copolymers The requirement for large quantities of saline to dissolve such materials limits their clinical use, and one solution for this problem that has recently generated interest is the formation of drug-loaded micelles.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719420/
Poly-lactic-co-glycolic acid (PLGA) has been the most successful polymeric biomaterial for use in controlled drug delivery systems. There are several different chemical and physical properties of PLGA that impact the release behavior of drugs from PLGA delivery devices.Author: Daniel J. Hines, David L. Kaplan
https://link.springer.com/article/10.1007%2Fs11095-009-9919-x
Jun 17, 2009 · The development of particle-based carriers for transepidermal drug delivery has become a field of major interest in dermatology. In this study, we investigated the suitability of biodegradable poly-lactic acid (PLA) particles loaded with fluorescent dyes as carriers for transepidermal drug delivery. The penetration profiles of PLA particles (228 and 365 nm) and the release of dye from the ...Author: Fiorenza Rancan, Dimitrios Papakostas, Sabrina Hadam, Steffen Hackbarth, Thierry Delair, Charlotte P...
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