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https://www.sciencedirect.com/science/article/pii/S0169409X16302113
Polylactic acid (PLA) and its copolymers have a long history of safety in humans and an extensive range of applications. PLA is biocompatible, biodegradable by hydrolysis and enzymatic activity, has a large range of mechanical and physical properties that can be engineered appropriately to suit multiple applications, and has low immunogenicity.Author: Betty Mae Tyler, David Gullotti, Antonella Mangraviti, Tadanobu Utsuki, Henry Brem
https://link.springer.com/article/10.1007%2Fs11095-009-9919-x
Jun 17, 2009 · The development of particle-based carriers for transepidermal drug delivery has become a field of major interest in dermatology. In this study, we investigated the suitability of biodegradable poly-lactic acid (PLA) particles loaded with fluorescent dyes as carriers for transepidermal drug delivery. The penetration profiles of PLA particles (228 and 365 nm) and the release of dye from the ...Author: Fiorenza Rancan, Dimitrios Papakostas, Sabrina Hadam, Steffen Hackbarth, Thierry Delair, Charlotte P...
https://www.ncbi.nlm.nih.gov/pubmed/27426411
Moved Permanently. The document has moved here.Author: Betty Mae Tyler, David Gullotti, Antonella Mangraviti, Tadanobu Utsuki, Henry Brem
https://link.springer.com/chapter/10.1007/12_2017_11
Apr 23, 2017 · These properties make PLA a promising polymer for biomedical applications. This review introduces the specific characteristics of PLA that enable its application for controlled drug delivery and describes different forms of PLA used for drug delivery, including nanoparticles, microspheres, hydrogels, electrospun fibers, and scaffolds.Author: Jiannan Li, Jiannan Li, Jianxun Ding, Tongjun Liu, Jessica F. Liu, Lesan Yan, Xuesi Chen
http://www.jocpr.com/articles/recent-applications-of-polylactic-acid-in-pharmaceutical-and-medical-industries.pdf
PLA has gained the attention in many applications due to its organics source[8,9].The properties and prospects in various recent synthesis techniques as well as the applications of PLA in biomedical, clinical, injury management and drug delivery system will be highlighted in this review. Figure 1 show the cycle of PLA in nature. Fig. 1.
https://www.sciencedirect.com/science/article/pii/S0264127519307749
The proposed 3D printed drug delivery system can simultaneously realize individual local chemotherapy, multi-drug delivery, long-term sustainable drug release, and non-reoperation in osteosarcoma treatment. Our studies enable the utilization of the 3D printing technique in the treatment of osteosarcomas and guide future clinical trials.Author: Yonghui Wang, Liang Sun, Zhigang Mei, Fazhou Zhang, Meifang He, Cameron Fletcher, Fenglong Wang, Jin...
https://www.researchgate.net/publication/12126032_Biodegradable_poly_lactic_acid_microspheres_for_drug_delivery_systems
Biodegradable poly (lactic acid) microspheres for drug delivery systems.pdf. Available via license: CC BY-NC 3.0. Content may be subject to copyright. Download full-text PDF.Author: Suong-Hyu Hyon
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347861/
Sep 01, 2011 · It is the best defined biomaterial available for drug delivery with respect to design and performance. Poly lactic acid contains an asymmetric α-carbon which is typically described as the D or L form in classical stereochemical terms and sometimes as R and S form, respectively. The enantiomeric forms of the polymer PLA are poly D-lactic acid ...Author: Hirenkumar K. Makadia, Steven J. Siegel
http://www.nanomedicine-rj.com/article_36899_3938552e42b8d8b2c36d8824d8d5b252.pdf
of PLA and Poly (Glycolic Acid) (PGA) that are most usually used biodegradable synthetic polymers for bio-medical uses for instance scaffolds and drug-delivery systems. The objective of this review paper is to highpoint the possibility of PLA nano-fibres as drug-delivery substances and to …Author: Farnaz Fattahi, Akbar Khoddami, Ozan Avinc
https://pubs.acs.org/doi/10.1021/mp500512z
Monitoring of drugs in vivo has been recognized as an urgent need for successful chemotherapy treatment. However, to find an appropriate tool for this purpose has been proved as a great challenge. Here, we report a PLA–PEG coated hollow X-ray and upconversion nanophosphor with folic acid as a tumor targeting ligand for a novel drug delivery system.Author: Hongyu Chen, Susan He
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