Physiological Barriers To The Oral Delivery Of Curcumin

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Physiological barriers to the oral delivery of curcumin.

    https://www.ncbi.nlm.nih.gov/pubmed/22822540
    The actual intestinal physiological barriers limiting curcumin absorption after oral administration have not been fully investigated. To identify the main barriers curtailing its absorption, in vitro permeability of curcumin and flux of its glucuronide were monitored in rat jejunum and Transwell grown Caco-2 cells.Author: Berginc K, Trontelj J, Basnet Ns, Kristl A

Physiological barriers to the oral delivery of curcumin ...

    https://www.researchgate.net/publication/229555044_Physiological_barriers_to_the_oral_delivery_of_curcumin
    Still one problem is physiological barriers (including a blood brain barrier) limiting curcumin absorption after oral or intravenous administrations [47]. This natural polyphenol was more ...

Physiological barriers to the oral delivery of curcumin ...

    https://www.ingentaconnect.com/content/govi/pharmaz/2012/00000067/00000006/art00009
    Jun 06, 2012 · The actual intestinal physiological barriers limiting curcumin absorption after oral administration have not been fully investigated. To identify the main barriers curtailing its absorption, in vitro permeability of curcumin and flux of its glucuronide were monitored in rat jejunum and Transwell grown Caco-2 cells. Curcumin was more permeable ...

Development and Evaluation of an In Vitro Vaginal Model ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513450/
    Aug 17, 2012 · Development and Evaluation of an In Vitro Vaginal Model for Assessment of Drug’s Biopharmaceutical Properties: Curcumin. ... Bovine vaginal mucosa was selected as surrogate for human tissue owing to anatomical, physiological ... Berginc K, Trontelj J, Skalko-Basnet N, Kristl B. The physiological barriers to oral delivery of curcumin. Die ...Author: Katja Berginc, Nataša Škalko-Basnet, Purusotam Basnet, Albin Kristl

Physiological barriers to the oral delivery of curcumin - CORE

    https://core.ac.uk/display/41035974
    The actual intestinal physiological barriers limiting curcumin absorption after oral administration have not been fully investigated. To identify the main barrierscurtailing its absorption, in vitro permeability of curcumin and flux of its glucuronide were monitored in rat jejunum and Transwell grown Caco-2 cells.

Advances and applications of chitosan-based nanomaterials ...

    https://www.sciencedirect.com/science/article/pii/S0141813020315105
    Nevertheless, the oral uptake efficiency of many therapeutic agents was limited by physiological barriers of the gastrointestinal (GI) tract. This review summarized the challenges toward the oral delivery systems including instability and poor permeability in gastrointestinal environment.

Chitosan/alginate nanoparticles as a promising approach ...

    https://www.sciencedirect.com/science/article/pii/S0928493117326346
    Use of chitosan/alginate nanoparticles for oral delivery of curcumin and its prodrugs has been reported [, , , ], but a systematic study of encapsulation of CG for enhancing the intestinal absorption and anticancer activity has not been performed. Therefore, the aims of this study were to fabricate CG-loaded chitosan/alginate nanoparticles and ...Author: Feuangthit Niyamissara Sorasitthiyanukarn, Chawanphat Muangnoi, Pahweenvaj Ratnatilaka Na Bhuket, Po...

Enhancing Curcumin Oral Bioavailability Through ...

    https://link.springer.com/article/10.1007%2Fs13318-019-00545-z
    Feb 15, 2019 · Other miscellaneous systems discussed include inorganic nanoparticles, micelles, solid nanodispersions, phytosomes, and dendrimers. The possibility of using intact nanoparticles to achieve the targeted oral delivery of curcumin and thus harness the benefits of this wonder nutraceutical is an exciting prospect.Author: Vinod S. Ipar, Anisha Dsouza, Padma V. Devarajan

Curcumin and cancer: barriers to obtaining a health claim ...

    https://academic.oup.com/nutritionreviews/article/73/3/155/1837697
    Feb 12, 2015 · Curcumin and cancer: barriers to obtaining a health claim Jessay G. Devassy. ... rates in cancer patients. 45–47 The modulation of antioxidant and free-radical activity is a complex biochemical and physiological interaction that has limited semblance to observations during in vitro experiments 44; ... Novel curcumin oral delivery systems.Author: Jessay G. Devassy, Ifeanyi D. Nwachukwu, Peter J.H. Jones

(PDF) Oral delivery of curcumin: Via porous polymeric ...

    https://www.researchgate.net/publication/316751932_Oral_delivery_of_curcumin_Via_porous_polymeric_nanoparticles_for_effective_ulcerative_colitis_therapy
    Oral delivery of curcumin: Via porous polymeric nanoparticles for effective ulcerative colitis therapy Article (PDF Available) in Journal of Materials Chemistry B 5(29) · May 2017 with 103 Reads

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