Photosensitizer Drug Delivery Via An Optical Fiber

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Photosensitizer Drug Delivery via an Optical Fiber

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329778/
    May 25, 2011 · An optical fiber has been developed with a maneuverable mini-probe tip that sparges O 2 gas and photo-detaches pheophorbide (sensitizer) molecules. Singlet oxygen is produced at the probe tip surface which reacts with an alkene spacer group releasing sensitizer upon …Author: Matibur Zamadar, Goutam Ghosh, Adaic kapillai Mahendran, Mihaela Minnis, Bonnie I Kruft, Ashwini Gho...

Photosensitizer Drug Delivery via an Optical Fiber ...

    https://pubs.acs.org/doi/abs/10.1021/ja200840p
    An optical fiber has been developed with a maneuverable mini-probe tip that sparges O2 gas and photodetaches pheophorbide (sensitizer) molecules. Singlet oxygen is produced at the probe tip surface which reacts with an alkene spacer group releasing sensitizer upon fragmentation of a dioxetane intermediate. Optimal sensitizer photorelease occurred when the probe tip was loaded with 60 nmol ...Author: Matibur Zamadar, Goutam Ghosh, Adaic kapillai Mahendran, Mihaela Minnis, Bonnie I Kruft, Ashwini Gho...

Photosensitizer Drug Delivery via an Optical Fiber ...

    https://www.researchgate.net/publication/51095268_Photosensitizer_Drug_Delivery_via_an_Optical_Fiber
    Photosensitizer Drug Delivery via an Optical Fiber Article in Journal of the American Chemical Society 133(20):7882-91 · May 2011 with 91 Reads How we measure 'reads'

Photosensitizer drug delivery via an optical fiber.

    https://www.ncbi.nlm.nih.gov/pubmed/21539365
    May 25, 2011 · Photosensitizer drug delivery via an optical fiber. Zamadar M(1), Ghosh G, Mahendran A, Minnis M, Kruft BI, Ghogare A, Aebisher D, Greer A. Author information: (1)Department of Chemistry and Graduate Center, City University of New York, Brooklyn College, Brooklyn, New York 11210, USA.Author: Matibur Zamadar, Goutam Ghosh, Adaic kapillai Mahendran, Mihaela Minnis, Bonnie I Kruft, Ashwini Gho...

Abstract 3234: Fiber optic-guided photosensitizer drug ...

    https://www.researchgate.net/publication/273658645_Abstract_3234_Fiber_optic-guided_photosensitizer_drug_delivery
    Abstract 3234: Fiber optic-guided photosensitizer drug delivery Article in Cancer Research 71(8 Supplement):3234-3234 · July 2011 with 9 Reads How we measure 'reads'

Faculty Profile Brooklyn College

    http://www.brooklyn.cuny.edu/web/academics/faculty/faculty_profile.jsp?faculty=576
    Brooklyn College is an integral part of the civic, ... One research area deals in the pioneering use of fiber optics combined with sensitizer drugs for the production and precise delivery of singlet oxygen to eradicate cancer cells. We also study the interfacial behavior of reactive oxygen species, including the localized delivery of singlet ...

“Pointsource” Delivery of a Photosensitizer Drug and ...

    http://europepmc.org/articles/PMC4198175
    Pointsource device for targeted singlet oxygen delivery: (a) Red laser light and oxygen gas traveled through the hollow fiber optic and emerged from the probe tip. We used 200 mW output from a 669 nm laser and a O 2 gas flow rate of ~0.2 ppm min 1 through the probe tip. The probe tip was held vertically in a perpendicular orientation above the ...

Polymeric Photosensitizer Prodrugs for Photodynamic ...

    http://onlinelibrary.wiley.com/doi/10.1111/j.1751-1097.2007.00090.x/abstract
    A targeting strategy based on the selective enzyme‐mediated activation of polymeric photosensitizer prodrugs (PPP) within pathological tissue has led to the development of agents with the dual ability...

A Hand-held Fiber-optic Implement for the Site-specific ...

    http://europepmc.org/articles/PMC3336966
    At present, fiber optics are available in endoscopic applications (3–6), but no point-specific fiber-based 1 O 2 generator exists as an alternative PDT.Fiber optic intubation methods exist that can deliver drugs through a catheter to a sensor probe tip, such as delivery of propranolol to the gastrointestinal tract in 40 m m concentrations (7,8) which exceed what is needed for sensitizer ...

CV for Dr - Stephen F. Austin State University

    https://orion.sfasu.edu/courseinformation/cv/1939.pdf
    CV for Dr. Matibur Zamadar EDUCATION ... Drug Delivery via an Optical Fiber” J. Am. Chem. Soc. 2011, 133, 7882-7891. ... photosensitizer/fiber optic device for on-site singlet oxygen generation” 238th American Chemical Society National Conference, Washington DC, August,

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