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https://www.sciencedirect.com/science/article/pii/S000186861630392X
Intraperitoneal delivery of phage was found to result in delivery of higher phage dose, delivered earlier into the blood and other tissues, and delivered for a more sustained period of time. Capparelli et al. [29] intravenously infected mice with S. aureus (dose, 10 8 CFU/mouse) followed by immediate intravenous injection of phage (10 7 , 10 8 ...Author: Danish J. Malik, Ilya J. Sokolov, Gurinder K. Vinner, Francesco Mancuso, Salvatore Cinquerrui, Goran...
https://www.sciencedaily.com/releases/2018/07/180717094813.htm
Jul 17, 2018 · "Phage delivery is an area where the right type of material could make a difference in therapeutic applications," said Andrés García, the Rae S. and Frank H. …
https://www.tandfonline.com/doi/full/10.1080/10717544.2017.1410259
Dec 01, 2017 · Phage enables target-selective delivery in several pathways: Firstly, the phage displayed with the target-specific peptides or antibodies can be used as nanocarriers of chemical drugs or gene drugs. Secondly, the phage displayed with target-specific peptides or antibodies can be conjugated with other vehicles (such as liposomes, inorganic ...Author: Zhigang Ju, Wei Sun
http://perspectivesinmedicine.cshlp.org/content/4/1/a012518.full
Others have also explored the oral delivery route of phage vaccination, and showed antigen-specific response (Delmastro et al. 1997; Zuercher et al. 2000). These results indicate the possibility of oral delivery of phage vaccine in developing countries.
https://mbio.asm.org/content/11/2/e00019-20
Apr 28, 2020 · We next sought to demonstrate that phage-mediated delivery of a genome-targeting CRISPR could enhance wild-type phage activity to more efficiently kill a target population of C. difficile.Given the efficacy of the genome-targeting CRISPR, we moved the leader-driven repeat-spacer-repeat construct onto the genome of the C. difficile bacteriophage ϕCD24-2 (the CRISPR-enhanced …Author: Kurt Selle, Joshua R. Fletcher, Hannah Tuson, Daniel S. Schmitt, Lana McMillan, Gowrinarayani S. Vri...
https://mediphagelab.com/
Nucleic acid delivery vectors and production systems. The bacteriophage PY54 Tel/pal recombinase system has been exploited as a novel platform for the efficient production of linear covalently closed (LCC) DNA minivectors, termed DNA ministrings, to serve as safe and effective DNA delivery vectors.
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