Peroral Delivery

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Peroral - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/chemistry/peroral
    Oral delivery. Peroral administration represents the most common and patient compliant route of drug administration, although some of the drugs have poor pharmacokinetic profiles when administered orally. The major barriers in oral delivery include the enzymes in the upper parts of the gastrointestinal (GI) system, the pH changes in the GI tract, absorption and efficient permeability across the intestinal wall, …

Intraoral Delivery is a Better Route - Life Enhancement ...

    https://life-enhancement.com/pages/intraoral-delivery-is-a-better-route
    W ithin the oral cavity (the mouth), the delivery of nutritional supplements and nutraceuticals may be categorized three ways: 1) Intraoral sublingual, which is systemic delivery through the mucosal membranes lining the floor of the mouth under the tongue, 2) Intraoral buccal, which is administration through the mucosal membranes lining the cheeks (buccal mucosa), and 3) Peroral, which is …

Peroral definition of peroral by Medical dictionary

    https://medical-dictionary.thefreedictionary.com/peroral
    Junginger, "Niosomes as a novel peroral vaccine delivery system," International Journal of Pharmaceutics, vol. Niosome: A Promising Nanocarrier for Natural Drug Delivery through Blood-Brain Barrier Panchagnula, "In situ and in vivo efficacy of peroral absorption enhancers in rats and correlation to in vitro mechanistic studies," Farmaco, vol.

Nanomicelle Based Peroral Delivery System for Enhanced ...

    https://www.ncbi.nlm.nih.gov/pubmed/26349302
    An effective sustained-release peroral drug delivery system is needed for chemotherapy. Here, we show that such a system can be achieved by designing polymeric nanomicelles combining mucoadhesion, enhanced absorption and controlled release.Author: Tian Y, Shi C, Zhang X, Sun Y, Wang J, Zhang Y, Yang J, Wang L, Mao S

Peroral delivery of insulin using chitosan derivatives: A ...

    https://www.sciencedirect.com/science/article/pii/S0378517307003808
    Polymeric delivery systems based on nanoparticles (NP) have emerged as a promising approach for peroral insulin delivery. Using a trimethyl chitosan (TMC) and a PEG-graft-TMC copolymer, polyelectrolyte complexes (PEC) and nanoparticles were prepared and their properties were compared.The amount of insulin was quantified by HPLC and the stability of PEC and NP upon …Author: Anchalee Jintapattanakit, Anchalee Jintapattanakit, Varaporn B. Junyaprasert, Shirui Mao, Shirui Mao...

Improved peroral delivery of glucagon-like peptide-1 by ...

    https://www.sciencedirect.com/science/article/pii/S0939641107002639
    Peptide oral delivery is still a significant challenge because of two major impediments, low absorption efficiency and instability in gastrointestinal tract.Author: Yu Seok Youn, Su Young Chae, Seulki Lee, Min Jung Kwon, Han Jong Shin, Kang Choon Lee

PLGA nanoparticles for peroral delivery: How important is ...

    https://www.sciencedirect.com/science/article/pii/S0939641116304489
    These findings prove that PLGA nanoparticles have the potential to enhance the systemic absorption in oral drug delivery. In addition, PLGA nanoparticles have also been used to improve the local treatment of colonic diseases , , , , , . Colonic delivery aims to avoid the systemic uptake in …Author: Anika Mante, Martha Heider, Christin Zlomke, Karsten Mäder

A review on the strategies for oral delivery of proteins ...

    https://www.sciencedirect.com/science/article/pii/S1319016414000590
    Oral delivery is the most sought after route of administration for most of the drugs and pharmaceutical products, which depends on the drug’s molecular structure or weight (Elsayed et al., 2009).Author: Abdul Muheem, Faiyaz Shakeel, Mohammad Asadullah Jahangir, Mohammed Anwar, Neha Mallick, Gaurav Kuma...

Peroral - definition of peroral by The Free Dictionary

    https://www.thefreedictionary.com/peroral
    Define peroral. peroral synonyms, peroral pronunciation, peroral translation, English dictionary definition of peroral. adj. Through or by way of the mouth: a peroral infection; peroral administration of fluids. per·o′ral·ly adv. adj med administered through the mouth;...

Peroral drug delivery system for peptides and proteins ...

    https://www.researchgate.net/publication/285130281_Peroral_drug_delivery_system_for_peptides_and_proteins
    The peroral administration of (poly)peptide drugs requires the development of delivery systems, which provide a protective effect toward a gastrointestinal enzymatic attack. A promising strategy...

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