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https://www.sciencedirect.com/science/article/pii/S0022354915497886
Research Articles Percutaneous Absorption and Dermal Delivery of Cyclosporin A Hoo†Kyun Choi, * ‡ x Gordon L. Flynn, * Gordon L. Amidon, * * College of Pharmacy, The University of Michigan, Ann Arbor, MI 48109†1065 College of Pharmacy, The University of Michigan Ann Arbor MI 48109†1065 ‡ Merck Research Laboratories, P.O. Box 4, West Point, PA 19486 Merck Research ...Author: Hoo‐Kyun ‐K Choi, Hoo‐Kyun ‐K Choi, Gordon L. Flynn, Gordon L. Amidon
https://www.sciencedirect.com/science/article/abs/pii/S0022354915497886
Percutaneous Absorption and Dermal Delivery of Cyclosporin A. ... Cyclosporin A in an ethanol/water formulation was then placed in the donor cell, with the amount of ethanol being controlled to maintain the highest possible thermodynamic activity. Accumulations of cyclosporin A in receiver cell media, aqueous or ethanol/water, were then assessed.Author: Hoo‐Kyun ‐K Choi, Hoo‐Kyun ‐K Choi, Gordon L. Flynn, Gordon L. Amidon
http://europepmc.org/abstract/MED/7658348
Jun 01, 1995 · Accumulations of cyclosporin A in receiver cell media, aqueous or ethanol/water, were then assessed. Permeation from two different concentrations of cyclosporin A was compared. The permeability of hairless mouse skin to cyclosporin A was increased by the pretreatment, but results with human skin were more equivocal.Author: Hoo‐Kyun ‐K Choi, Hoo‐Kyun ‐K Choi, Gordon L. Flynn, Gordon L. Amidon
https://jamanetwork.com/journals/jamadermatology/fullarticle/2516220
Jul 01, 2016 · Percutaneous absorption and dermal delivery of cyclosporin A. ... Amarji B, et al. Efficacy of Novel Topical Liposomal Formulation of Cyclosporine in Mild to Moderate Stable Plaque Psoriasis: A Randomized Clinical Trial. ... Percutaneous absorption and dermal delivery of cyclosporin A. ...Author: Rajiv Kumar, Sunil Dogra, Basant Amarji, Bhupinder Singh, Suresh Kumar, Sharma, Keshavamurthy Vinay,...
http://onlinelibrary.wiley.com/doi/10.1002/jps.2600840513/abstract
Sep 17, 2006 · Previous article in issue: Percutaneous absorption and dermal delivery of cyclosporin A. Previous article in issue: Percutaneous absorption and dermal delivery of cyclosporin A Next article in issue: Experimental evaluation of a model for predicting micellar composition and concentration of monomeric species in bile salt binary mixtures
https://www.mdpi.com/2079-4991/9/9/1204/htm
Cyclosporin A (CsA) is a nonribosomal cyclic peptide with eleven amino acids, identified and recovered from Tolypocladium inflatum.Until 1983 was the only immunosuppressant agent to be commercialized as Sandimmune ® and later Neoral ®.It is a powerful immunosuppressive agent widely used in the therapy of skin-related diseases, namely psoriasis, atopic dermatitis, and alopecia aerata, and ...Author: Abderrazzaq Essaghraoui, Ahmed Belfkira, Bassou Hamdaoui, Cláudia Nunes, Sofia A. Costa Lima, Salett...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910788/
Sep 30, 2019 · They are used for dermal and transdermal delivery of molecules since they can penetrate the stratum corneum . However, percutaneous absorption and penetration of lipophilic 8MOP in intact skin are poor. After the development of microemulsions about 20 years ago, more recently nanocarriers were investigated for improved drug supply of 8MOP.Author: Uwe Wollina, Michael Tirant, Aleksandra Vojvodic, Torello Lotti
http://www.authorstream.com/Presentation/nils2311-838043-percutaneous-absorption-3/
Feb 16, 2011 · Percutaneous absorption is a more complicated process which is takes place in two phases, 1.Epidermal diffusion 2.Clearance from the dermis.-it is depends on effective blood flow, interstitial fluid movement , lymphatic and dermal constituents.
https://www.deepdyve.com/lp/elsevier/effect-of-vehicles-and-enhancers-on-the-topical-delivery-of-vX30Rd3n69
Mar 27, 2006 · Read "Effect of vehicles and enhancers on the topical delivery of cyclosporin A, International Journal of Pharmaceutics" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs.Author: Mark R Prausnitz, Robert Langer
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