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https://www.researchgate.net/publication/11811755_Percutaneous_absorption_and_delivery_systems
Here, the main challenge is to address the transdermal delivery of drugs because there will be a variability in the percutaneous absorption due to site, disease, age and etc. Skin irritation may ...
https://www.cidjournal.com/article/S0738-081X(01)00183-3/pdf
Percutaneous Absorption and Delivery Systems PIERFRANCESCO MORGANTI, PhD ELEONORA RUOCCO, MD RONNI WOLF, MD VINCENZO RUOCCO, MD I n recent years, two of the main problems confront-ing cosmetic chemists have been to obtain the ab-sorption of cosmetic products through the skin layer, and to prove their clinical efficacy. In fact, the
http://www.scielo.br/pdf/bjps/v52n3/2175-9790-bjps-52-03-00527.pdf
novel drug delivery systems are necessary to characterize their quality and efficacy. This review covers the most well-known methods for assessing the cutaneous absorption of drugs as an auxiliary tool for pharmaceutical formulation scientists in the design of drug delivery systems. In vitro methods as skinFile Size: 879KB
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086417/
4. Challenges in Topical Delivery. The greatest challenge for dermal penetration is the tough horny layer, that is, stratum corneum (SC), the uppermost layer of the skin, which is the rate limiting step for epidermal drug transport [].The physicochemical factors of drug like log P, pK a, solubility, and molecular mass also play an important role in the selection of components for the topical ...Author: Kaisar Raza, Manish Kumar, Pramod Kumar, Ruchi Malik, Gajanand Sharma, Manmeet Kaur, O. P. Katare
https://www.researchgate.net/publication/44480907_Dermatological_formulations_percutaneous_absorption_Brian_W_Barry
Dermatological formulations : percutaneous absorption / Brian W. Barry ... also known as penetration enhancers, percutaneous absorption promoters or ... based delivery systems for transdermal ...
https://www.sciencedirect.com/science/article/pii/037851738390145X
International Journal of Pharmaceutics. 16 ( 1983) 255-270 255 Eisevier Review Article Percutaneous absorption: possibilities and problems Jonathan Hadgraft Department of Pharmacy, University of Nottingham, University Park.Author: Jonathan Hadgraft
https://link.springer.com/chapter/10.1007/978-94-009-1291-5_11
Transdermal drug delivery systems are topical devices designed originally to deliver a potent drug to the surface of the skin at a controlled rate. This rate was intended to be well below the maximum...Author: B. W. Barry
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161196/
Lanolin-Based Synthetic Membranes as Percutaneous Absorption Models for Transdermal Drug Delivery. ... but complex model systems and the simple models. The challenge here is to develop models that lend themselves to both molecular-level experiments and simulations. ... and the transepidermal water loss and percutaneous absorption of three ...Author: Victor Carrer, Beatriz Guzmán, Meritxell Martí, Cristina Alonso, Luisa Coderch
https://www.cidjournal.com/article/S0738-081X(01)00183-3/abstract
In recent years, two of the main problems confronting cosmetic chemists have been to obtain the absorption of cosmetic products through the skin layer, and to prove their clinical efficacy. In fact, the interference caused by all the products topically applied to the skin, mainly on the intercellular lipids of the stratum corneum (SC) but also on the cellular membrane of all the viable skin ...Author: Pierfrancesco Morganti, Eleonora Ruocco, Ronni Wolf, Vincenzo Ruocco
https://www.sciencedirect.com/science/article/pii/S0378517309008047
Bicellar systems for in vitro percutaneous absorption of diclofenac. ... Percutaneous absorption studies demonstrated a lower penetration of DDEA when the drug was included in bicellar systems than when the drug was applied in an aqueous solution. This effect was possibly due to a certain rigidity of the bicellar systems caused by the ...Author: L. Rubio, C. Alonso, G. Rodríguez, L. Barbosa-Barros, L. Coderch, A. De la Maza, J.L. Parra, O. Lópe...
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