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https://www.researchgate.net/publication/7892201_Peptide-oligonucleotide_conjugates_for_the_delivery_of_antisense_and_siRNA
Peptide-oligonucleotide conjugates for the delivery of antisense and siRNA Article · Literature Review in Current opinion in molecular therapeutics 7(2):132-6 · May 2005 with 66 Reads
https://www.ncbi.nlm.nih.gov/pubmed/15844620
Peptide-oligonucleotide conjugates for the delivery of antisense and siRNA. Juliano RL(1). Author information: (1)University of North Carolina, Department of Pharmacology, School of Medicine, Chapel Hill, NC 27599, USA. [email protected]: Rudolph L. Juliano
https://www.lifetein.com/Peptide-oligonucleotide-conjugate.html
LifeTein Peptide oligonucleotide conjugate: DNA-Peptide and RNA-Peptide. Oligonucleotide-peptide conjugates are chimeric molecules composed of a nucleic acid moiety covalently linked to a peptide moiety. It is an important tool for studies of the protein– and peptide–nucleic acid interactions, as well as being promising bioconjugates for ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390225/
Jun 12, 2012 · Juliano RL. Peptide-oligonucleotide conjugates for the delivery of antisense and siRNA. Curr Opin Mol Ther. 2005; 7:132–136. Nakase I, Akita H, Kogure K, Gräslund A, Langel U, Harashima H. et al. (2011 Efficient intracellular delivery of nucleic acid pharmaceuticals using cell-penetrating peptides Acc Chem Res epub ahead of print).Author: Peter Järver, Thibault Coursindel, Samir El Andaloussi, Samir El Andaloussi, Caroline Godfrey, Matth...
https://www.biosyn.com/sirna-peptide-conjugates.aspx
While intracellular delivery of these siRNA oligomers has been the focus of numerous research groups worldwide, chemical conjugation of siRNA to cationic peptide CPP (cell-penetrating peptides) or penetrating provides an interesting approach for enhancing antisense …
https://www.sciencedirect.com/science/article/pii/S1079979606002038
Towards the development of oligonucleotide analogues and siRNA as drugs, one potential alternative to the use of liposomal transfection agents is the covalent conjugation of a cell-penetrating peptide (CPP), with the intention of imparting on the oligonucleotide or siRNA an enhanced ability to enter mammalian cells and reach the appropriate RNA target.Author: John J. Turner, Simon Jones, Martin M. Fabani, Gabriela Ivanova, Andrey A. Arzumanov, Michael J. Gai...
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