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Peptide-MediatedTargeted Drug Delivery Sumit Majumdar and Teruna J. Siahaan Department of Pharmaceutical Chemistry, The University of Kansas, Simons Research Laboratories, 2095 Constant Ave., Lawrence, Kansas 66047 DOI 10.1002/med.20225. Abstract: Targeted drug delivery to specific group of cells offers an attractive strategy to minimize the
https://www.researchgate.net/publication/46125443_Peptide-mediated_targeted_drug_delivery
Targeted drug delivery to specific group of cells offers an attractive strategy to minimize the undesirable side effects and achieve the therapeutic effect with a lower dose.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679013/
To date, studies on targeted drug delivery for breast cancer have largely centered on pre-clinical studies using anti-HER2 antibody-linked liposomal drugs , . However, few reports have studied the use of peptides for targeted drug delivery in breast cancer treatment , .Author: Ruei-Min Lu, Min-Shan Chen, Min-Shan Chen, De-Kuan Chang, Chien-Yu Chiu, Wei-Chuan Lin, Shin-Long Ya...
https://onlinelibrary.wiley.com/doi/abs/10.1002/med.20225
Targeted drug delivery to specific group of cells offers an attractive strategy to minimize the undesirable side effects and achieve the therapeutic effect with a lower dose. Both linear and cyclic peptides have been explored as trafficking moiety due to ease of synthesis, structural simplicity, and low probability of undesirable immunogenicity.Author: Sumit Majumdar, Teruna J. Siahaan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598503/
Mar 12, 2013 · Peptide ligands have played an important role in tumor-targeted drug delivery as targeting moieties. The in vivo fate of peptide-mediated drug delivery systems and the following antitumor effects may greatly depend on the stability of the peptide ligand.Author: Chong Li, Yixin Wang, Xiaolin Zhang, Li Deng, Yan Zhang, Zhangbao Chen
https://www.biosyn.com/literaturevault/peptide-mediated-targeted-drug-delivery.aspx#!
Abstract: Targeted drug delivery to specific group of cells offers an attractive strategy to minimize the undesirable side effects and achieve the therapeutic effect with a lower dose.Both linear and cyclic peptides have been explored as trafficking moiety due to ease of synthesis, structural simplicity, and low probability of undesirable immunogenicity.
https://pubs.acs.org/doi/10.1021/mp500086e
This article is cited by 43 publications. Juan Guan, Zhuxuan Jiang, Mengke Wang, Ying Liu, Jican Liu, Yang Yang, Tianhao Ding, Weiyue Lu, Chunli Gao, Jun Qian, Changyou Zhan. Short Peptide-Mediated Brain-Targeted Drug Delivery with Enhanced Immunocompatibility.Author: Xiaoli Wei, Changyou Zhan, Xishan Chen, Jiapeng Hou, Cao Xie, Weiyue Lu
https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.8b01216
Peptide ligands have been exploited as versatile tools to facilitate targeted delivery of nanocarriers. However, the effects of peptide ligands on immunocompatibility and therapeutic efficacy of liposomes remain intricate. Here, a short and stable brain targeted peptide ligand D8 was modified on the surface of doxorubicin-loaded liposomes (D8-sLip/DOX), demonstrating prolonged blood ...Author: Juan Guan, Zhuxuan Jiang, Mengke Wang, Ying Liu, Jican Liu, Yang Yang, Tianhao Ding, Weiyue Lu, Chun...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0066128
Targeted delivery of drugs to tumors represents a significant advance in cancer diagnosis and therapy. Therefore, development of novel tumor-specific ligands or pharmaceutical nanocarriers is highly desirable. In this study, we utilized phage display to identify a new targeting peptide, SP90, which specifically binds to breast cancer cells, and recognizes tumor tissues from breast cancer ...Author: Ruei-Min Lu, Min-Shan Chen, Min-Shan Chen, De-Kuan Chang, Chien-Yu Chiu, Wei-Chuan Lin, Shin-Long Ya...
https://www.dovepress.com/a54-peptide-mediated-functionalized-gold-nanocages-for-targeted-delive-peer-reviewed-article-IJN
A54 peptide-mediated functionalized gold nanocages for targeted delivery of DOX as a combinational photothermal-chemotherapy for liver cancer Shengnan Huang,1,* Chunming Li,2,* Weiping Wang,1 Huanjie Li,1 Zhi Sun,3 Chengzhi Song,4 Benyi Li,5 Shaofeng Duan,6,7 Yurong Hu1,8,9 1Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases, School of Pharmaceutical Sciences, …Author: Shengnan Huang, Chunming Li, Weiping Wang, Huanjie Li, Zhi Sun, Chengzhi Song, Benyi Li, Shaofeng Du...
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