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https://www.sciencedirect.com/science/article/pii/B9780123849359100100
The most commonly used cell-penetrating peptides (CPPs): Tat, oligoarginine, and transportan, have all been demonstrated to facilitate the entry of protein/peptide cargoes into cells both in vitro and in vivo.Author: Helin Räägel, Margus Pooga, Margus Pooga
https://www.nature.com/articles/nbt1201-1173
Dec 01, 2001 · A peptide carrier for the delivery of biologically active proteins into mammalian cells Skip to main content Thank you for visiting nature.com.Author: May C. Morris, Julien Depollier, Jean Mery, Frederic Heitz, Gilles Divita
https://www.sciencedirect.com/science/article/pii/S0960894X17311952
Cell penetrating peptides (CPPs), which are 8–30 amino acids long with cationic or amphipathic sequences, can efficiently deliver membrane impermeable bioactive macromolecules such as peptides, proteins, and oligonucleotides into cells.1, 2 Generally, CPP-conjugated macromolecules (CPP–cargos) enter cells by various modes of endocytosis. 1 However, CPP–cargos often get trapped in the …Author: Hyungjin Kim, Mizuki Kitamatsu, Takashi Ohtsuki
https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201904894
Aug 12, 2019 · The scarcity of effective means to deliver functional proteins to living cells is a central problem in biotechnology and medicine. Herein, we report the efficient delivery of an active DNA‐modifying enzyme to human stem cells through high‐density cell penetrating peptide …Author: Angela P. Blum, David A. Nelles, Francisco J. Hidalgo, Mollie A. Touve, Deborah S. Sim, Assael A. Ma...
https://www.nature.com/articles/s41598-019-39211-4
Feb 28, 2019 · One of the critical challenges in PNA technology is their delivery to cells 27, in particular their low uptake by eukaryotic cells 28,29,30,31,32. In order to solve this drawback, several ...Author: Jessica Gasparello, Alex Manicardi, Alex Manicardi, Alessandro Casnati, Roberto Corradini, Roberto G...
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