Peptide Based Gene Delivery System

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Peptide-Based Autophagic Gene and Cisplatin Co-delivery ...

    https://pubs.acs.org/doi/10.1021/acs.nanolett.9b00083
    Cisplatin-based chemotherapy is a widely used first-line strategy for numerous cancers. However, drug resistances are often inevitable accompanied by the long-term use of cisplatin in vivo, significantly hampering its therapeutic efficacy and clinical outcomes. Among others, autophagy induction is one of the most common causes of tumor resistance to cisplatin. Herein, a self-assembled ...Author: Yao-Xin Lin, Yao-Xin Lin, Yi Wang, Yi Wang, Yi Wang, Hong-Wei An, Baowen Qi, Junqing Wang, Lei Wang,...

Insight into the mechanism of the peptide-based gene ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC156720/
    Jun 01, 2003 · The improvement of non-viral-based gene delivery systems is of prime importance for the future of gene and antisense therapies. We have previously described a peptide-based gene delivery system, MPG, derived from the fusion peptide domain of HIV-1 gp41 protein and the nuclear localisation sequence (NLS) of SV40 large T antigen.Author: Federica Simeoni, May C. Morris, Frederic Heitz, Gilles Divita

(PDF) Peptide-Based and Polypeptide-Based Gene Delivery ...

    https://www.researchgate.net/publication/314459487_Peptide-Based_and_Polypeptide-Based_Gene_Delivery_Systems
    For cancer gene therapy to be feasible and viable in a clinical setting, the design and development of a suitable gene delivery system is imperative. Peptide based vectors, in particular, reveal ...

(PDF) An over view: Protein and peptide based drug delivery

    https://www.researchgate.net/publication/319122467_An_over_view_Protein_and_peptide_based_drug_delivery
    An over view: Protein and peptide based drug delivery. ... The first approach in ocular drug delivery system is that to . prolong the contact time by incorporating various . polymers .

Characterization of a multifunctional PEG-based gene ...

    https://www.sciencedirect.com/science/article/pii/S1742706108002924
    Characterization of a multifunctional PEG-based gene delivery system containing nuclear localization signals and endosomal escape peptides ☆ Author links open overlay panel Nicole M. Moore a c Clayton L. Sheppard b Shelly E. Sakiyama-Elbert a b cAuthor: Nicole M. Moore, Clayton L. Sheppard, Shelly E. Sakiyama-Elbert

Self-Assembled Peptide-Based System for Mitochondrial ...

    https://www.ncbi.nlm.nih.gov/pubmed/27696822
    Nov 14, 2016 · Self-Assembled Peptide-Based System for Mitochondrial-Targeted Gene Delivery: Functional and Structural Insights. Chuah JA(1), Matsugami A(2), Hayashi F(2), Numata K(1). Author information: (1)Enzyme Research Team, Biomass Engineering Research Division, Center for Sustainable Resource Science, RIKEN , 2-1 Hirosawa, Wako-shi, Saitama 351-0198, JapanAuthor: Jo-Ann Chuah, Akimasa Matsugami, Fumiaki Hayashi, Keiji Numata

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