Peptide-Based Cationic Liposome-Mediated Gene Delivery

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Peptide-based cationic liposome-mediated gene delivery

    https://www.researchgate.net/publication/51818700_Peptide-based_cationic_liposome-mediated_gene_delivery
    This review hopes to provide some suggestions on the design of peptide cationic lipids and insight into their development trend in the field of gene delivery. Expert opinion: As peptide-based ...

Peptide-based cationic liposome-mediated gene delivery ...

    https://www.tandfonline.com/doi/abs/10.1517/17425247.2011.630387
    Introduction: As an important type of nonviral gene delivery vector, peptide-based cationic liposomes have shown many advantages over other cationic liposomes, such as good biodegradability, excell...Author: Yinan Zhao, Shubiao Zhang, Shaohui Cui, Bing Wang, Shufen Zhang

Toxicological exploration of peptide-based cationic ...

    https://www.ncbi.nlm.nih.gov/pubmed/30947085
    Jul 01, 2019 · The toxicology of cationic liposomes was explored to advance clinical trials of liposome-mediated gene therapy through the analysis of a peptide cationic liposome with DOTAP as a positive control. We first investigated the delivery of luciferase siRNA by several peptide liposomes in mice bearing lung cancer A549 cell xenografts.Author: Yanyan Zhu, Yanyan Zhu, Yao Meng, Yinan Zhao, Jie Zhu, Hong Xu, Enxia Zhang, Lei Shi, Linying Du, Gu...

Cationic Polymer Based Gene Delivery Systems SpringerLink

    https://link.springer.com/article/10.1023%2FA%3A1007548826495
    Feb 01, 2000 · Cationic Polymer Based Gene Delivery Systems. ... Pulmonary surfactant inhibits cationic liposome-mediated gene delivery to respiratory epithelial cells in vitro. Hum. ... E. Tomlinson, J. T. Sparrow, and L. C. Smith. A physicochemical approach for predicting the effectiveness of peptide-based gene delivery systems for use in plasmid-based gene ...Author: Stefaan C. De Smedt, Joseph Demeester, Wim E. Hennink

Toxicological exploration of peptide-based cationic ...

    https://www.sciencedirect.com/science/article/pii/S0927776519302012
    The in vivo siRNA delivery as mediated by the cationic peptide-based liposomes was first investigated in mice. Then, we explored the toxicological mechanisms underlying liposome delivery. Lastly, we demonstrated the potential utility of the cationic peptide-based liposome for gene delivery.Author: Yanyan Zhu, Yanyan Zhu, Yao Meng, Yinan Zhao, Jie Zhu, Hong Xu, Enxia Zhang, Lei Shi, Linying Du, Gu...

Hybrids of Nonviral Vectors for Gene Delivery ...

    https://pubs.acs.org/doi/10.1021/bc900261c
    Peptide-based cationic liposome-mediated gene delivery. Expert Opinion on Drug Delivery 2012, 9 (1) , 127-139. DOI: 10.1517/17425247.2011.630387. Adarsha Koirala, Rasha S. Makkia, Mark J. Cooper, Muna I. Naash. Nanoparticle-mediated gene transfer specific to retinal pigment epithelial cells.Author: Shubiao Zhang, Yinan Zhao, Budiao Zhao, Bing Wang

Lipid-mediated delivery of RNA is more efficient than ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849731/
    Apr 15, 2010 · The design of appropriate gene delivery systems is essential for the successful application of gene therapy to clinical medicine. Cationic lipid-mediated delivery is a viable alternative to viral vector-mediated gene delivery in applications where transient gene expression is desirable.Author: S. Zou, K. Scarfo, M.H. Nantz, J.G. Hecker

(PDF) Liposomes as a gene delivery system - ResearchGate

    https://www.researchgate.net/publication/12950633_Liposomes_as_a_gene_delivery_system
    Liposomes as a gene delivery system Article · Literature Review (PDF Available) in Brazilian Journal of Medical and Biological Research 32(2):163-9 · March 1999 with 3,337 Reads

Lipophilic Peptides for Gene Delivery Bioconjugate Chemistry

    https://pubs.acs.org/doi/10.1021/bc700451b
    DNA transfections are widely performed in research laboratories and in vivo gene delivery holds the promise for curing many diseases. The synthetic carriers or vectors for DNA are typically cationic lipids. However, in biology, the recognition of nucleic acids by proteins involves both electrostatic and stacking contributions. As such we have prepared a series of new lipophilic peptide vectors ...Author: Carla A. H. Prata, Xiao-Xiang Zhang, Dan Luo, Thomas J. McIntosh, Philippe Barthelemy, Mark W. Grins...

Intraperitoneal gene delivery mediated by a novel cationic ...

    http://www.nature.com/articles/doi:10.1038/sj.gt.3301704
    Jun 18, 2002 · The efficiency of normal cationic liposome-mediated gene expression often decreases with the addition of serum.26 It is ... Efficacy of a peptide-based gene delivery system depends on mitotic ...Author: Min Jae Lee, S. S. Cho, J. R. You, Y. Lee, B. D. Kang, J. S. Choi, J. W. Park, Y. L. Suh, J. A. Kim,...

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