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https://www.sciencedirect.com/science/article/pii/S1359644605035750
PEGylation of red blood cells (RBCs) at the level of membrane proteins, carbohydrates or lipid head groups was devised mainly for transfusion purposes, but also for the preparation of stealth RBCs useful as drug delivery system .Author: Francesco M. Veronese, Gianfranco Pasut
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051498/
Polyethylene glycol (PEG) is widely utilized in drug delivery and nanotechnology due to its reported “stealth” properties and biocompatibility. It is generally thought that PEGylation allows particulate delivery systems and biomaterials to evade the immune system and thereby prolong circulation lifetimes.Author: Johan J. F. Verhoef, Thomas J. Anchordoquy
https://www.sciencedirect.com/science/article/pii/S1818087615000860
However, recent preclinical studies of anti-cancer drug enclosed in PEGylated liposomes in rodents and dogs have shown the rapid blood clearance of the pegylated drug carrier system due to the increased anti-PEG-IgM production , . An example of PEGylated liposomal formulations, PEGylated liposomal doxorubicin (PLD), and most extensively studied ...Author: Prajna Mishra, Bismita Nayak, R.K. Dey
https://www.nature.com/articles/s41598-020-59624-w
Feb 17, 2020 · Schematic illustration of co-delivery of Pt and DOX by PEGylated nano-graphene oxide for improving anticancer activity. (A) The synthesis of pGO-Pt/DOX dual-drug delivery system…Author: Xibo Pei, Zhou Zhu, Zhoujie Gan, Junyu Chen, Xin Zhang, Xinting Cheng, Qianbing Wan, Jian Wang
https://www.sciencedaily.com/releases/2010/03/100311101612.htm
Mar 13, 2010 · The Melbourne-based research team has shown how PEGylated polylysine dendrimers, a new type of nano-sized drug delivery system, can be altered to target either the lymphatic system …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518266/
Enhanced anti-ischemic stroke of ZL006 by T7-conjugated PEGylated liposomes drug delivery system. ... The enhanced accumulation of T7-P-LPs in brain encouraged us to use it as a targeting drug delivery system for ZL006 to treat ischemic stroke. Figure 7. The in vivo BBB penetration ability of coumarin-6-labeled T7-P-LPs and P-LPs.Author: Zhongyuan Wang, Yue Zhao, Yan Jiang, Wei Lv, Lin Wu, Baoyan Wang, Lingyan Lv, Qunwei Xu, Hongliang X...
https://www.worldscientific.com/doi/abs/10.1142/S1793984416420022
In addition, utilization of PEG in DDS are reported with enhanced delivery efficiency, prolonged circulation time and improved stability, especially active enzymes and peptides drug delivery. In this paper, we will conclude current studies about Pegylated DDS and their biomedical applications from both in …Author: Fei Liu, Yuan Sun, Chen Kang, Hongyan Zhu
https://www.researchgate.net/publication/332257118_Pegylated_Drug_Delivery_Systems
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https://pubs.rsc.org/en/content/articlelanding/2020/bm/c9bm01927h
In order to improve active tumor targeting, tumor cell uptake efficiency and circulation time of doxorubicin (DOX) in vivo, we constructed a cleavable PEGylated hyaluronic acid nano-drug delivery system (HA–mPEG2k–DOX) based on a tumor microenvironment pH-responsive imine bond. In this study, HA–mPEG2k–DOX can selfAuthor: Xinyu Zhang, Minyi Zhao, Nan Cao, Wei Qin, Meng Zhao, Jun Wu, Dongjun Lin
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