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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664963/
Dec 01, 2015 · Advances and Challenges of Liposome Assisted Drug Delivery. ... the clinical translation of liposome assisted drug delivery platforms has progressed incrementally. In this review, we will discuss the advances in liposome assisted drug delivery, biological challenges that still remain, and current clinical and experimental use of liposomes for ...Author: Lisa Sercombe, Tejaswi Veerati, Tejaswi Veerati, Fatemeh Moheimani, Sherry Y. Wu, Anil K. Sood, Susa...
https://www.sciencedirect.com/science/article/pii/S0005273612002179
Based on these findings, various surface modification approaches have been investigated to develop effective liposome-based drug delivery systems. Since PEG is a highly hydrophilic polymer with very low toxicity, PEG and its derivatives have been widely used to improve the stability and pharmacokinetics of drug carriers and parent drugs .Author: Koji Nakamura, Keiko Yamashita, Yuki Itoh, Keisuke Yoshino, Shigenori Nozawa, Hiroaki Kasukawa
https://www.sciencedirect.com/science/article/pii/S0168365914004556
PEG — A versatile conjugating ligand for drugs and drug delivery systems. ... A simple system uses specific linkers or bond to form PEG drug conjugates that are hydrolyzed by the acidic pH of endosome and releases active drug moiety; B) double prodrug system: Utilizes two linker moieties for PEGylation where first drug linker is released from ...Author: Atul Kolate, Dipesh Baradia, Sushilkumar Patil, Imran Vhora, Girish Kore, Ambikanandan Misra
https://onlinelibrary.wiley.com/doi/full/10.1002/adhm.201901489
Extending our approach to liposome‐mediated, intracellular drug delivery, we first measured the in vitro cytotoxicity (MDA‐MB 231 cells, WST assay) of doxorubicin‐filled E PEG ‐ and F PEG ‐liposomes (4 mol% PEG 5000), before and after light activation, and compared this …Author: Li Kong, Quanchi Chen, Frederick Campbell, Ewa Snaar‐Jagalska, Alexander Kros
https://www.sciencedaily.com/releases/2017/10/171023180627.htm
Oct 23, 2017 · Liposomes are successful drug delivery vehicles prescribed for several types of cancer but also for treatment of fungal infections or pain management. Now researchers show a …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426795/
Moreover, PEG grafted onto the liposome surface can guide the liposome to a specific intracellular target, using for example cell-penetrating proteins and peptides as targeting agents. The development of liposome delivery to particular subcellular compartments is a field of great interest in different fields, such as gene therapy and vaccination.Author: Maria Laura Immordino, Franco Dosio, Luigi Cattel
https://www.researchgate.net/publication/322814419_Liposomes_Clinical_Applications_and_Potential_for_Image-Guided_Drug_Delivery
efforts on developing image drug delivery systems are still ongoing with the intent of obtaining better diagnosis and therapy of different diseases. PET labeling of liposomes is an effort at ...
https://www.researchgate.net/publication/281063035_Liposomes_as_a_Drug_Delivery_System
Liposomes as a Drug Delivery System. ... Schematic representation of an engineered liposome for long circulation and ligand/Ab-mediated targeted delivery. (Reproduced with permission from K. Sen ...
https://www.youtube.com/watch?v=EjtVVLK-O14
Jan 03, 2017 · The evolution of the science and technology of liposomes has been used in the development of drug carrier concept as a promising delivery system. The liposome was adopted as a promising delivery ...Author: Piramal Pharma Solutions
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