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https://www.ncbi.nlm.nih.gov/pubmed/16296766
This review presents an overview of studies concerning oral formulations intended for site-specific drug delivery to the colon with pectin as the main excipient. The biological aspects covered include gastrointestinal transit and the enzymatic degradation of pectin.Author: Sverre Arne Sande
https://www.tandfonline.com/doi/abs/10.1517/17425247.2.3.441
Jan 12, 2007 · This review presents an overview of studies concerning oral formulations intended for site-specific drug delivery to the colon with pectin as the main excipient. The biological aspects covered include gastrointestinal transit and the enzymatic degradation of pectin.Author: Sverre Arne Sande
https://www.sciencedirect.com/science/article/pii/S0142961203002138
Studies showed that the optimal weight ratio of high methoxyl pectin in the composite is 10–15%. This weight percent of pectin provides the best solute release kinetics with respect to colon-specific drug delivery. The attack of pectinolytic enzymes initiates pectin degradation and its release.Author: LinShu Liu, Marshall L. Fishman, Joseph Kost, Kevin B. Hicks
https://www.researchgate.net/publication/7471389_Pectin-based_oral_drug_delivery_to_the_colon
This review presents an overview of studies concerning oral formulations intended for site-specific drug delivery to the colon with pectin as the main excipient. The biological aspects covered...
https://www.sigmaaldrich.com/catalog/papers/16296766
This review presents an overview of studies concerning oral formulations intended for site-specific drug delivery to the colon with pectin as the main excipient. The biological aspects covered include gastrointestinal transit and the enzymatic degradation of pectin.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066368/
Pectin is suitable for use as colon-specific drug delivery vehicle in treatment of colon cancer and other colon diseases as it is selectively digested by microflora in colon and exhibits potential to prevent colon cancer from the implication of diet . Being a soluble dietary fiber, pectin is reported to increase the transit time through gastrointestinal tract, fecal bulk, bile acid excretion and short-chain fatty acid …Author: Tin Wui Wong, Gaia Colombo, Fabio Sonvico
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