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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756366/
1. Introduction. The success of a gene therapy will largely depend on the activity induced by the target genes and the efficiency of gene delivery resulting from the combined effects of the delivery vector and the applied delivery route (Figure 1).Here we present a narrative review that summarizes the recent knowledge on the use of gene therapy for the treatment of pancreatic cancer.Author: Cristina Fillat, Anabel Jose, Xavier Bofill-Deros, Ana Mato-Berciano, Maria Victoria Maliandi, Lucia...
https://www.mdpi.com/2072-6694/3/1/368/htm
The continuous identification of molecular changes deregulating critical pathways in pancreatic tumor cells provides us with a large number of novel candidates to engineer gene-targeted approaches for pancreatic cancer treatment. Targets—both protein coding and non-coding—are being exploited in gene therapy to influence the deregulated pathways to facilitate cytotoxicity, enhance the ...Author: Cristina Fillat, Anabel Jose, Xavier Bofill-Deros, Ana Mato-Berciano, Maria Victoria Maliandi, Lucia...
https://www.mdpi.com/2072-6694/3/1/368
The continuous identification of molecular changes deregulating critical pathways in pancreatic tumor cells provides us with a large number of novel candidates to engineer gene-targeted approaches for pancreatic cancer treatment. Targets—both protein coding and non-coding—are being exploited in gene therapy to influence the deregulated pathways to facilitate cytotoxicity, enhance the ...Author: Cristina Fillat, Anabel Jose, Xavier Bofill-Deros, Ana Mato-Berciano, Maria Victoria Maliandi, Lucia...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188890/
Oct 07, 2014 · Core tip: This paper tries to present a full picture of gene therapy in pancreatic cancer, providing an unambiguous classification and comprehensive analysis, especially in therapeutic targets and clinical trials worldwide. From our work, you may find the hotspots in related research and the reason why they get there.Author: Si-Xue Liu, Zhong-Sheng Xia, Ying-Qiang Zhong
https://www.researchgate.net/publication/258429403_Pancreatic_Cancer_Gene_Therapy_From_Molecular_Targets_to_Delivery_Systems
Pancreatic Cancer Gene Therapy: From Molecular Targets to Delivery Systems Article (PDF Available) in Cancers 3(1):368-95 · December 2011 with 401 Reads How we measure 'reads'
http://www.oalib.com/paper/150809
The continuous identification of molecular changes deregulating critical pathways in pancreatic tumor cells provides us with a large number of novel candidates to engineer gene-targeted approaches for pancreatic cancer treatment. Targets—both protein codin...
https://www.researchgate.net/publication/265715619_Gene_Therapy_for_Treatment_of_Pancreatic_Cancer
In the present review, an overview of principles behind use of gene therapy including molecular targets, various delivery vectors and gene therapy approaches in context to pancreatic cancer ...
https://www.mdpi.com/2072-6694/3/1/368/notes
Metabolic Disorder, Inflammation, and Deregulated Molecular Pathways Converging in Pancreatic Cancer Development: Implications for New Therapeutic Strategies ... Rational and Irrational Issues in Breast Cancer Screening. ... Dependence of Relative Expression of NTR1 and EGFR on Cell Density and Extracellular pH in Human Pancreatic Cancer Cell ...Author: Cristina Fillat, Anabel Jose, Xavier Bofill-Deros, Ana Mato-Berciano, Maria Victoria Maliandi, Lucia...
https://www.nature.com/articles/cgt201273
Oct 26, 2012 · Pancreatic cancer (PC) is the fourth leading cause of cancer death among men and women, comprising 6% of all cancer-related death. 1 The …Author: V Lisiansky, V Lisiansky, I Naumov, I Naumov, S Shapira, S Shapira, D Kazanov, A Starr, A Starr, N A...
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(19)30372-5
Nov 25, 2019 · MicroRNAs (miRNAs) are endogenous small noncoding RNAs that negatively regulate gene expression by interfering with the translation or stability of target transcripts. Some tumor-suppressive miRNAs can concurrently target multiple cancer-promoting genes and may be useful as therapeutic anticancer agents. However, the development of drug delivery systems is critical for the …Author: Kentaro Gokita, Jun Inoue, Hiroshi Ishihara, Kazuyuki Kojima, Johji Inazawa
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