Pancreatic Cancer Drug Delivery

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Targeted Drug Delivery in Pancreatic Cancer

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815202/
    The most commonly used carriers for drug delivery in pancreatic cancer treatment include liposomes, nanoparticles, and carbon nanotubes. Those carriers can protect the drugs from degradation and will effectively deliver them to the target organs.

Targeted drug delivery in pancreatic cancer - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/S0304419X09000729
    The most commonly used carriers for drug delivery in pancreatic cancer treatment include liposomes, nanoparticles, and carbon nanotubes . These carriers can protect the drugs from degradation and will effectively deliver them to the target organs.Author: Xianjun Yu, Yuqing Zhang, Changyi Chen, Qizhi Yao, Min Li

Pancreatic Cancer: Pathobiology, Treatment Options, and ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844509/
    Mar 03, 2010 · Drug Delivery in Pancreatic Cancer . Chemotherapeutic agents are often administered systemically; thus, drug delivery to a tumor involves several processes including transport within a vessel, transport across the vessel wall into surrounding tissues, and transport through interstitial space within a tumor . Each process is affected by both the physicochemical properties of the drug…Author: Jing Li, M. Guillaume Wientjes, Jessie L.-S. Au

New strategy to improve drug delivery to pancreatic tumors ...

    https://www.pancan.org/research/strategic-research-program/news/new-strategy-to-improve-drug-delivery-to-pancreatic-tumors/
    Since chemotherapeutics and other cancer drugs are administered intravenously, the poor blood supply to pancreatic tumors also impedes drug delivery. A mouse model of pancreatic cancer that Dr. Hingorani helped develop mimics this feature of human pancreatic cancer.

PanTher’s drug-delivery patch takes aim at the ‘wall’ of ...

    https://www.statnews.com/2018/12/14/panther-therapeutics-patch-pancreatic-cancer/
    Dec 14, 2018 · Startup Spotlight: PanTher’s drug-delivery patch aims to knock down the ‘wall’ of pancreatic cancer. Wherever there has been a stage for biotech entrepreneurs this fall, Laura Indolfi …

Disrupting Pancreatic Cancer pH May Hold Therapeutic Potential

    https://www.genengnews.com/news/disrupting-pancreatic-cancer-ph-may-hold-therapeutic-potential/
    Apr 08, 2020 · “Pancreatic cancer is predicted to soon become the second-leading cause of cancer-related deaths in the U.S.,” noted Cosimo Commisso, PhD, assistant professor at Sanford Burnham Prebys Cancer ...

Chemotherapy nanoparticles offer breakthrough in ...

    http://pancreatic.org/chemotherapy-nanoparticles-offer-breakthrough-in-pancreatic-cancer-drug-delivery/
    Apr 18, 2017 · Pancreatic ductal adenocarcinoma is generally a fatal disease, with a five-year survival rate of less than 6 percent. The introduction of nanocarriers as delivery vehicles for common chemotherapy agents such as the drug irinotecan, has led …

Controlled drug delivery vehicles for cancer treatment and ...

    https://www.nature.com/articles/s41392-017-0004-3
    Mar 16, 2018 · Alginate-PAMAM dendrimer-based hybrid nanogels have been developed for drug delivery to cancer cells, and they showed pH-dependent release behavior in a sustained way 131. Nanocarriers have been ...Author: Sudipta Senapati, Arun Kumar Mahanta, Sunil Kumar, Pralay Maiti

Inducing enhanced immunogenic cell death with nanocarrier ...

    https://www.sciencedirect.com/science/article/pii/S0142961216302861
    Nanoparticle-encapsulated drugs (nanocarrier-drug delivery systems) comprise the therapeutic entities, such as chemotherapeutic drugs and therapeutic siRNA , , , , and the nanocarriers formed by biocompatible materials, such as polymers and liposomes , , , , .Author: Xiao Zhao, Xiao Zhao, Keni Yang, Ruifang Zhao, Tianjiao Ji, Xiuchao Wang, Xiao Yang, Yinlong Zhang, ...

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