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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017392/
Apr 18, 2018 · Multiple drug delivery systems: PAMAM dendrimers were evaluated to explore the potential of PAMAM dendrimers for multiple drug delivery. We have entrapped two anti-hypertensive drugs Ramipril (RAPL) and hydrochlorothiazide (HCTZ ). The results showed that the solubility of RAPL and HCTZ was dependent on dendrimer concentrations and pH of ...Author: Abhay Singh Chauhan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278347/
Nov 02, 2018 · These results can be useful for designing strategies regarding dendrimer-based pulmonary drug delivery . Anionic PAMAM dendrimers and dextran probes, two polymers containing similar molecular sizes, were analyzed by endocytic uptake in lung tissues. Both compounds were passively absorbed in the intact lung.Author: Renan Vinicius de Araújo, Soraya da Silva Santos, Elizabeth Igne Ferreira, Jeanine Giarolla
https://www.sciencedirect.com/science/article/pii/S2352940718301641
Targeted PAMAM dendrimer for co-delivery of a drug and siRNA. (a) Doxorubicin and siRNA against major vault protein (MVP), plus hyaluronic acid (as a targeting agent) were conjugated to PAMAM dendrimer. (b) Hyaluronic acid interacted with its receptor CD44. (c) Complex was taken up by receptor-mediated endcytosis.Author: Fereydoon Abedi-Gaballu, Fereydoon Abedi-Gaballu, Gholamreza Dehghan, Maryam Ghaffari, Maryam Ghaffa...
https://www.sciencedirect.com/science/article/pii/S0079670013000853
Thiagarajan et al. assessed oral drug delivery aptitude of 6.5 G PAMAM dendrimers via in vivo oral translocation in CD-1 mice with evaluation of acute oral toxicity and physicochemical disposition and concluded that dendrimers have the potential to permeate gut epithelial barrier .Author: Prashant Kesharwani, Keerti Jain, Narendra Kumar Jain
https://en.wikipedia.org/wiki/Poly(amidoamine)
Poly(amidoamine), or PAMAM, is a class of dendrimer which is made of repetitively branched subunits of amide and amine functionality.PAMAM dendrimers, sometimes referred to by the trade name Starburst, have been extensively studied since their synthesis in 1985, and represent the most well-characterized dendrimer family as well as the first to be commercialized.
https://www.hindawi.com/journals/jnm/2014/507273/
In recent years, the application of dendrimers in biomedicine attracted much attention from scientists. Dendrimers are interesting for biomedical applications because of their characteristics, including: a hyperbranching, well-defined globular structures, excellent structural uniformity, multivalency, variable chemical composition, and high biological compatibility. In particular, the three ...Author: B. Noriega-Luna, Luis A. Godínez, Francisco J. Rodríguez, A. Rodríguez, G. Zaldívar-Lelo de Larrea, ...
http://www.dendritech.com/pamam.html
34 rows · The term "dendrimer" was derived from its tree-like branching structure. The tables below …
https://www.sigmaaldrich.com/materials-science/material-science-products.html?TablePage=16375655
Applications of dendrimers Applications highlighted in recent literature include drug delivery, gene transfection, catalysis, energy harvesting, photo activity, molecular weight and size determination, rheology modification, and nanoscale science and technology. 1, 2 Dendrimer synthesis
https://www.mdpi.com/1420-3049/23/4/938/pdf
branches. As a drug delivery scientist, it is imperative to understand the architecture of dendrimers. 2. Discussion 2.1. Dendrimer-Drug Delivery Strategy PAMAM dendrimers were first reported by Tomalia in 1985 [3,4]. PAMAM dendrimers are one of the most used dendrimers for drug delivery systems [5–7]. The dendrimer architecture has three mainAuthor: Abhay Singh Chauhan
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