We have collected information about Osteoarthritis And Drug Delivery for you. Follow the links to find out details on Osteoarthritis And Drug Delivery.
https://www.ncbi.nlm.nih.gov/pubmed/29792929
To satisfy this unmet medical need, drug delivery systems (DDSs) containing disease-modifying OA drugs (DMOADs) for intra-articular (IA) administration are required to improve the health of OA patients. DDSs should provide controlled and/or sustained drug release, enabling long-term treatment with a reduced number of injections.Author: Pierre Maudens, Olivier Jordan, Eric Allémann
https://www.sciencedirect.com/science/article/pii/S1359644618300461
Schematic representation of the retention time and clearance of various biodegradable osteoarthritis (OA) drug delivery systems (DDSs) after intra-articular (IA) administration. Free drugs, hydrogel, nanoparticles and microparticles remain in the joint for hours, days, weeks and months, respectively.Author: Pierre Maudens, Olivier Jordan, Eric Allémann
https://www.drugs.com/condition/osteoarthritis.html
76 rows · Osteoarthritis is a painful condition of the joints that becomes more common with age. It is …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015522/
Introduction. Intra-articular (IA) drug delivery presents many advantages as it offers direct access to …
https://www.hindawi.com/journals/jnt/2012/748909/
The objective of this paper is to provide readers with current developments of intra-articular drug delivery systems. In recent years, although the search for a clinically successful ideal carrier is ongoing, sustained-release systems, such as polymeric micro- and nanoparticles, liposomes, and hydrogels, are being extensively studied for intra-articular drug delivery purposes. The advantages ...Author: Zhiyue Zhang, Guihua Huang
https://www.ncbi.nlm.nih.gov/pubmed/28202920
Current intra-articular drug delivery methods do not guarantee sufficient drug penetration into cartilage tissue to reach cell and matrix targets at the concentrations necessary to elicit the desired biological response. Here, we provide our perspective on the utilization of charge-charge (electrostatic) interactions to enhance drug penetration ...Author: Ambika G. Bajpayee, Alan J. Grodzinsky
https://www.oarsijournal.com/article/S1063-4584(15)01295-9/fulltext
In the current issue of Osteoarthritis and Cartilage, Bajpayee et al. 1 x 1 Bajpayee, A.G., Quadir, M.A., Hammond, P.T., and Grodzinsky, A.J. Charge based intra-cartilage delivery of single dose dexamethasone using Avidin nano-carriers suppresses cytokine-induced catabolism long term. Osteoarthritis Cartilage. 2015;Author: Christopher H Evans
https://www.tandfonline.com/doi/abs/10.1517/17425247.2014.867325
Jan 09, 2009 · Introduction: Intra-articular (IA) drug delivery is very useful in the treatment of osteoarthritis (OA), the most common chronic joint affliction. However, the therapeutic effect of IA administration depends mostly on the efficacy of drug delivery. Areas covered: The present article reviews the current status of IA therapy for OA treatment as well as its rationale.Author: Mi Lan Kang, Gun-Il Im
https://www.nature.com/articles/nrrheum.2016.210
Current osteoarthritis therapies cannot sufficiently target cartilage and guarantee a biological response owing to limitations in the delivery methods. This Perspectives article discusses how ...Author: Ambika G. Bajpayee, Alan J. Grodzinsky
https://www.nature.com/articles/s41584-018-0123-4
Nov 29, 2018 · Intra-articular drug delivery has a number of advantages over systemic administration; however, for the past 20 years, intra-articular treatment options for the management of knee osteoarthritis ...Author: Ian A. Jones, Ryan Togashi, Melissa L. Wilson, Nathanael Heckmann, C. Thomas Vangsness
Searching for Osteoarthritis And Drug Delivery?
You can just click the links above. The data is collected for you.
