We have collected information about Oral Protein And Peptide Drug Delivery for you. Follow the links to find out details on Oral Protein And Peptide Drug Delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792531/
Thus, we can achieve site-specific drug delivery by the use of mucoadhesive polymeric system. Mucoadhesive polymers are able to adhere to the mucin layer on the mucosal epithelium and thus results in the increase of oral drug bioavailability of protein and peptide drugs.
https://www.ondrugdelivery.com/review-oral-peptide-delivery/
PROTEIN ORAL DELIVERY TECHNOLOGY POD ™ POD technology developed by Oramed (Jerusalem, Israel), consists of enteric-coated capsules containing an oily suspension of the peptide drug, an enzyme inhibitor, such as soy bean trypsin inhibitor, aprotinin and an absorption enhancer such as EDTA or bile salt, in omega-3 fatty acids.
https://link.springer.com/content/pdf/10.1208%2Fs12249-019-1325-z.pdf
protein polypeptide drug. BARRIERS TO ORAL DELIVERY OF PROTEIN AND PEPTIDE DRUG NPS Most of the protein and peptide drugs are macromolec-ular hydrophilic, in the extreme environment of gastrointes-tinal stability, susceptible to gastric acid and pepsin degradation; at the same time, because of its hydrophilicity,Author: Shu-jun Cao, Shuo Xu, Hui-ming Wang, Yong Ling, Jiahua Dong, Rui-dong Xia, Xiang-hong Sun
https://www.researchgate.net/publication/40834786_Protein_and_Peptide_Drug_Delivery_Oral_Approaches
Designing means to deliver peptide and protein drugs successfully to the systemic circulation by the oral route has been a challenge to scientists in drug delivery for many years [1].
https://www.sciencedirect.com/science/article/pii/B9780128179093000169
In addition, PEG polymer is nontoxic, nonimmunogenic, and is widely available with extensive studies about its chemical and physical properties. These properties make the PEGylation a very attractive approach in designing oral protein and peptide delivery systems (Roberts et al., 2012, Veronese, 2001, Harris and Chess, 2003).Author: Pran Kishore Deb, Omar Al-Attraqchi, Balakumar Chandrasekaran, Anant Paradkar, Rakesh K. Tekade
https://www.ncbi.nlm.nih.gov/pubmed/20046732
The main challenge is to improve the oral bioavailability from less than 1% to at least 30-50%. Consequently, efforts have intensified over the past few decades, where every oral dosage form used for the conventional small molecule drugs has been used to explore oral protein and peptide delivery.Author: Jessy Shaji, V Patole
https://www.sciencedirect.com/science/article/pii/S1319016414000590
The current article deals with the possibilities being explored in the oral delivery of protein and peptide therapeutics, the challenges in their development and the current and future prospects, with focus on technology trends in the market to improve the bioavailability of proteins and peptides and effect of different forms of therapeutic ...Author: Abdul Muheem, Faiyaz Shakeel, Mohammad Asadullah Jahangir, Mohammed Anwar, Neha Mallick, Gaurav Kuma...
https://www.ijpsonline.com/articles/protein-and-peptide-drug-delivery-oral-approaches.html
Nov 10, 2006 · Chemical modification and use of mucoadhesive polymeric system for site-specific drug delivery seen to be promising candidates for protein and peptide drug delivery. References . Rick S. Oral protein and peptide drug delivery. In: Binghe W, Teruna S, Richard AS, editors. Drug delivery: Principles and applications.Author: Jessy Shaji, V Patole
https://www.slideshare.net/BrajeshKumar67/protein-and-peptide-drug
May 24, 2015 · protein and peptide drug delivery system 1. PROTEIN AND PEPTIDE DRUG DELIVERY SYSTEM PRESENTED BY BRAJESH KUMAR M. PHARM (1ST YEAR) PHARMACEUTICS BBAU LUCKNOW , 1 2. Contents I. Protein & Peptides II. Structure of protein III. Classification of protein IV. Drug delivery system V. Stability testing VI. Conclusion VII. References 2 3.
https://www.nature.com/articles/s41573-019-0053-0
Dec 17, 2019 · Oral delivery of peptide therapeutics could have benefits for treatment adherence, but it faces barriers related to the structural organization and physiological function of the gastrointestinal ...Author: Daniel J. Drucker
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