Oral Protein And Peptide Drug Delivery Ppt

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Protein and Peptide Drug Delivery: Oral Approaches

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792531/
    Designing oral peptide and protein delivery systems has been a persistent challenge to pharmaceutical scientists because of their several unfavorable physicochemical properties including large molecular size, susceptibility to enzymatic degradation, short plasma half-life, ion permeability, immunogenicity, and the tendency to undergo aggregation, adsorption, and denaturation 12,13. Consequently, the absolute …

(PDF) Protein and Peptide Drug Delivery: Oral Approaches

    https://www.researchgate.net/publication/40834786_Protein_and_Peptide_Drug_Delivery_Oral_Approaches
    When protein and peptide drugs pass through the stomach, a part of the drugs are hydrolyzed and lose their biological activity due to the complex pH environment of the whole gut (1, 33). The drug enters the system, the metabolism caused by various enzymes, especially the action of various forms of proteolytic enzymes,...

Protein and Peptide drug delivery: oral approaches.

    https://www.ncbi.nlm.nih.gov/pubmed/20046732
    The main challenge is to improve the oral bioavailability from less than 1% to at least 30-50%. Consequently, efforts have intensified over the past few decades, where every oral dosage form used for the conventional small molecule drugs has been used to explore oral protein and peptide delivery.Author: Jessy Shaji, V Patole

Protein and peptide drug delivery: Oral approaches

    https://www.ijpsonline.com/articles/protein-and-peptide-drug-delivery-oral-approaches.html
    Nov 10, 2006 · Chemical modification and use of mucoadhesive polymeric system for site-specific drug delivery seen to be promising candidates for protein and peptide drug delivery. References . Rick S. Oral protein and peptide drug delivery. In: Binghe W, Teruna S, Richard AS, editors. Drug delivery: Principles and applications.Author: Jessy Shaji, V Patole

Protein and Peptide Drug Delivery: Oral Approaches

    http://www.ijpsonline.com/articles/protein-and-peptide-drug-delivery-oral-approaches.pdf
    Protein and Peptide Drug Delivery: Oral Approaches JESSY SHAJI* AND V. PATOLE Department of Pharmaceutical Sciences, Prin. K. M. Kundnani College of Pharmacy, Cuffe Parade, Mumbai-400 005, India Shaji, et al.: Oral Delivery of Proteins and PeptidesAuthor: Jessy Shaji, V Patole

Protein/Peptide Drug Delivery Systems: Practical ...

    https://www.sciencedirect.com/science/article/pii/B9780128179093000169
    This chapter will discuss the basic concepts and problems of protein and peptide delivery systems with special emphasis on the most notable approaches used for development of protein and peptide drug delivery systems. 16.2. Structural Characteristics and Properties of Proteins and PeptidesAuthor: Pran Kishore Deb, Omar Al-Attraqchi, Balakumar Chandrasekaran, Anant Paradkar, Rakesh K. Tekade

PROTEIN AND PEPTIDE DRUG DELIVERY authorSTREAM

    http://www.authorstream.com/Presentation/pharmawick-1969759-protein-peptide-drug-delivery/
    Oct 24, 2013 · 8 Advantages of protein and peptide drug delivery system Erythropoietin used for production of RBC. Tissue plasminogen activator is used for Heart attack, Stroke. Oxytocin maintain labor pain. Bradykinin increases the peripheral circulation. Somatostatin decrease bleeding in gastric ulcer. Gonadotropin induce ovulation.

Protein And Peptide Drug Delivery System authorSTREAM

    http://www.authorstream.com/Presentation/gunjankapoor25-1285615-types-of-proteins-and-peptides/
    Dec 21, 2011 · Protein and peptide Protein are the most abundant macromolecule in the living cells. The name protein is coined from the greek word- Protos , meaning “first” or “foremost”. Proteins - Chains of same 20 amino acids but in different combinations and sequences, each joined together by a specific type of covalent bond.

protein and peptide drug delivery system - SlideShare

    https://www.slideshare.net/BrajeshKumar67/protein-and-peptide-drug
    May 24, 2015 · Number of approaches are available for effective protein and peptide drug delivery. They are IONTOPHORESIS PHONOPHORESIS PENETRATION ENHANCERS PRODRUG Iontophoresis: Used for local and systemic delivery of proteins and peptides. In this an electric current is used to drive the molecules across the skin surface.

Protein and peptide d d s - SlideShare

    https://www.slideshare.net/bharathpharmacist/protein-and-peptide-d-d-s
    Sep 30, 2014 · Number of approaches are available for effective protein and peptide drug delivery. They are IONTOPHORESIS PHONOPHORESIS PENETRATION ENHANCERS PRODRUG Iontophoresis: Used for local and systemic delivery of proteins and peptides. In this an electric current is used to drive the molecules across the skin surface.

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