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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737653/
Mar 01, 2013 · Oral insulin delivery has been an interesting and promising research field that promises to revolutionize the way diabetes mellitus is treated. Several studies have achieved some positive results, and some delivery systems are in advanced stages of development.Author: Pedro Fonte, Francisca Araújo, Salette Reis, Bruno Sarmento
https://www.diabetesnet.com/about-diabetes/insulin/insulin-delivery/oral-insulin-delivery/
Oral Insulin Delivery The development of an oral form of insulin has been a work in progress for many years. Many companies have decided to look for an oral form of insulin as this will help patients become more compliant with insulin therapy.
https://www.webmd.com/diabetes/features/insulin-delivery
Uneven insulin delivery. Because they send insulin into the body through the pores, jet injectors may not always deliver an accurate dose. Other options include an insulin patch. Work closely with your doctor to choose the option that best fits your budget, health needs, and lifestyle.
https://www.sciencedirect.com/science/article/pii/S0169409X98000751
This may have a role in the oral delivery of insulin as much of the digestive activity of gastric and pancreatic enzymes occurs early in the gastrointestinal tract. Polymers which have pH-dependent solubilities can be used to fabricate these spheres.Author: Beth A. Burnside, Carol E. Mattes, Charlotte M. McGuinness, Edward M. Rudnic, George W. Belendiuk
https://www.sciencedirect.com/book/9781907568473/oral-delivery-of-insulin
Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an introductory chapter on symptoms, complications and therapy for Diabetes Mellitus.
https://www.fiercebiotech.com/research/oral-insulin-finally-here-thanks-to-tortoise-inspired-drug-delivery-system
Feb 07, 2019 · An oral insulin delivery system inspired by tortoises Despite nearly a century of research, researchers have so far failed to develop an oral form of insulin …
https://www.ncbi.nlm.nih.gov/pubmed/29501738
May 05, 2018 · Oral insulin delivery, the challenge to increase insulin bioavailability: Influence of surface charge in nanoparticle system. Czuba E(1), Diop M(1), Mura C(1), Schaschkow A(1), Langlois A(1), Bietiger W(1), Neidl R(1), Virciglio A(1), Auberval N(2), Julien-David D(3), Maillard E(1), Frere Y(2), Marchioni E(3), Pinget M(1), Sigrist S(4).Author: Elodie Czuba, Mouhamadou Diop, Carole Mura, Anais Schaschkow, Allan Langlois, William Bietiger, Roma...
https://www.pnas.org/content/115/28/7296
Jul 10, 2018 · Insulin is currently available as an injectable formulation, but an oral product would enjoy higher patient compliance and would significantly improve the quality of life of diabetic patients worldwide. However, oral delivery of proteins such as insulin is challenging due to various gastrointestinal barriers to oral absorption of macromolecules.Author: Amrita Banerjee, Kelly Ibsen, Kelly Ibsen, Tyler Brown, Renwei Chen, Christian Agatemor, Samir Mitra...
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