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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474414/
Oral Gene Delivery for Gene Therapy Applications Delivery of genetic materials, such as plasmid DNA or siRNA [ 5 – 9 ], as well as combination therapies that deliver both genetic and pharmacological treatments [ 10 ], via the oral route, have been explored for the treatment of several diseases.Author: Eric Farris, Kari Heck, Anna T. Lampe, Deborah M. Brown, Amanda E. Ramer-Tait, Angela K. Pannier
https://biopharmadealmakers.nature.com/users/262926-engene/documents/49814-engene-june-2019
Jun 10, 2019 · Oral gene delivery is a revolutionary improvement over current protein-drug delivery methods which involve injections and represent risks of side …
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201701079
The oral administration of nonviral vectors for gene delivery must overcome various difficulties in their transport through the GI tract, such as the physical stability of the vectors under particular pH conditions, the protection of the carried pDNA in harsh GI environments, and the transcytosis of the vectors through the intestinal epithelium.Author: Po Yen Lin, Ya Ling Chiu, Ya Ling Chiu, Jing Huei Huang, Er Yuan Chuang, Fwu Long Mi, Kun Ju Lin, Jy...
https://www.nature.com/articles/nm0499_387
Oral gene delivery with chitosan–DNA nanoparticles generates immunologic protection in a murine model of peanut allergy Skip to main content Thank you for visiting nature.com.Author: Krishnendu Roy, Hai Quan Mao, Shau Ku Huang, Kam W. Leong
https://briefs.techconnect.org/wp-content/volumes/Nanotech2007v2/pdf/243.pdf
oral and systemic delivery of genes for vaccines and transient gene therapy of a range of diseases. Keywords: yeast cell wall particles, DNA delivery, layer by layer synthesis, encapsulated nanoparticles INTRODUCTION The methods of gene delivery can be classified into recombinant viruses and synthetic vectors, and in-depthAuthor: G Ostroff, E Soto
https://www.sciencedaily.com/releases/2008/05/080520163044.htm
May 22, 2008 · The most recent findings of the four-year project evaluating the efficiency of Nanoparticles-in-Microsphere Oral Systems (NiMOS) oral gene delivery system have just been published. The article...
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