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https://www.sciencedirect.com/science/article/pii/S0169409X12003535
The nanoparticles with peptidic ligands would be a promising candidate for oral protein delivery. The potential of nanoparticles in drug delivery has remained. Challenges to developing protein formulations for oral delivery are still significant, and the quest to overcome the problem is ongoing.Author: Yeonhee Yun, Yeonhee Yun, Yong Woo Cho, Kinam Park, Kinam Park
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322271/
May 01, 2012 · Oral delivery of nanoparticles is also being investigated for treatment and detection of cancers [122–124], so it is important to understand the effect of tumor presence on the mucosa. Mucins have a complex and integral role in tumor development.Author: Laura M. Ensign, Laura M. Ensign, Richard Cone, Richard Cone, Justin Hanes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574626/
Jun 15, 2013 · Targeted nanoparticles with peptidic ligands As stated earlier, there are a number of limitations to the oral delivery of proteins despite the progress of the knowledge in this field. The barriers to protein bioavailability after oral administration are intestinal membrane permeability, molecule size, intestinal and hepatic metabolism, and ...Author: Yeonhee Yun, Yeonhee Yun, Yong Woo Cho, Kinam Park, Kinam Park
https://www.sciencedirect.com/science/article/pii/S0168365916303819
1. Introduction. Oral ingestion remains the preferred mode of delivery for most drugs owing largely to simplicity. The oral route is associated with the greatest degree of patient compliance (especially for chronic conditions) as it ensures convenience, enables self-administration, and offers great flexibility in dosage regimen.Author: Abhijit A. Date, Justin Hanes, Laura M. Ensign, Laura M. Ensign
https://www.acs.org/content/acs/en/pressroom/presspacs/2018/acs-presspac-august-15-2018/oral-delivery-of-nanoparticles.html
“Oral Nanoparticles Exhibit Specific High-Efficiency Intestinal Uptake and Lymphatic Transport” ACS Nano. Nanoparticles show great promise as diagnostic tools and drug delivery agents.
https://www.nature.com/articles/s41551-019-0465-5
Anionic nanoparticles increase intestinal permeability and enable the oral delivery of proteins, as shown with the delivery of insulin in healthy, hyperglycaemic, and diabetic mice.Author: Nicholas G. Lamson, Adrian Berger, Katherine C. Fein, Kathryn A. Whitehead
https://www.understandingnano.com/nanoparticle-oral-drug-delivery.html
Polymer Nanoparticle for Oral Anticancer Drug Delivery. One of the problems that cancer patients face is that many of the most potent anticancer therapies can be administered only by injection, which means that cancer patients must travel to receive their medication.
https://link.springer.com/content/pdf/10.1208%2Fs12249-019-1325-z.pdf
Nanoparticles: Oral Delivery for Protein and Peptide Drugs Shu-jun Cao,1 Shuo Xu,2 Hui-ming Wang,3 Yong Ling,3 Jiahua Dong,3 Rui-dong Xia,1 and Xiang-hong Sun3,4 Received 6 October 2018; accepted 31 January 2019; published online 20 May 2019 Abstract. Protein and peptide drugs have many advantages, such as high bioactivity andAuthor: Shu-jun Cao, Shuo Xu, Hui-ming Wang, Yong Ling, Jiahua Dong, Rui-dong Xia, Xiang-hong Sun
https://pubs.acs.org/doi/10.1021/bm060065f
Recent Advancement of Chitosan-Based Nanoparticles for Oral Controlled Delivery of Insulin and Other Therapeutic Agents. AAPS PharmSciTech 2011, 12 (1) , 10-20. DOI: 10.1208/s12249-010-9561-2. Weizhong Yuan, Zhengda Zhao, Jinying Yuan, Shuying Gu, Fengbo Zhang, Xuming Xie, Jie Ren.Author: Feng Qian, Fuying Cui, Jieying Ding, Cui Tang, Chunhua Yin
https://www.researchgate.net/publication/232811914_Nanoparticles_for_oral_delivery_Targeted_nanoparticles_with_peptidic_ligands_for_oral_protein_delivery
[1][2] [3] As a promising new drug delivery technology, the utilization of polymeric nanoparticles for oral delivery of drugs can improve drug absorption efficacy by passing through intestinal ...
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