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https://www.sciencedirect.com/science/article/pii/0169409X94900264
Since there is a limit to the size of the bioadhesive ORAL CAVITY AS SITE FOR BIOADHESIVE DRUG DELIVERY 65 dosage form, only a limited amount of drug can be used in these systems. In general, any drug with a daily requirement of 25 mg or less would be a candidate for buccal delivery.Author: Rajesh B. Gandhi, Joseph R. Robinson
https://www.sciencedirect.com/science/article/abs/pii/0169409X94900264
Bioadhesive polymers can overcome the removal issue and can be coupled with penetration enhancers to generate a novel and successful delivery system for both local and systemic drug delivery. The present review examines factors influencing the disposition of drugs and delivery systems in the oral cavity as well as pertinent biological barriers.Author: Rajesh B. Gandhi, Joseph R. Robinson
https://www.researchgate.net/publication/232010943_Drug_Delivery_from_the_Oral_Cavity_A_Focus_on_Mucoadhesive_Buccal_Drug_Delivery_Systems
Drug Delivery from the Oral Cavity: A Focus on Mucoadhesive Buccal Drug Delivery Systems ... Mucoadhesive Buccal Drug Delivery Systems. ... formation for the development of bioadhesive drug.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255397/
Mucoadhesive drug delivery systems have applications from different angles, including development of novel mucoadhesives, design of the device, mechanisms of mucoadhesion and permeation enhancement. With the influx of a large number of new drug molecules due to drug discovery, mucoadhesive drug delivery will play an even more important role in ...
http://www.ijpmbs.com/uploadfile/2015/0412/20150412031556858.pdf
RECENT ADVANCES IN MUCOADHESIVE/ BIOADHESIVE DRUG DELIVERY SYSTEM: A REVIEW Phanindra B1*, B Krishna Moorthy1 and M Muthukumaran1 Review Article The current article has been focused on the mucoadhesive drug delivery system may be designed to enable prolonged retention at the site of application, providing a controlled rate of drug release
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161066/
1. Introduction. Drug delivery in the oral cavity can be divided into two main categories: systemic and local drug delivery. Effective drug delivery in the oral cavity is essential for the treatment of oral diseases in both soft and hard oral tissues (e.g., mucosal and enamel, respectively).Author: Apipa Wanasathop, S. Kevin Li
https://www.tandfonline.com/doi/abs/10.1081/DDC-52073
The oral mucosal cavity is a feasible, safe, and very attractive site for drug delivery with good acceptance by users. The mucosa is relatively permeable and robust, shows short recovery times after stress or damage, is tolerant to potential allergens, and has a rich blood supply.Author: Marcos Luciano Bruschi, Osvaldo de Freitas
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