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https://www.researchgate.net/publication/7905831_Oral_Bioadhesive_Drug_Delivery_Systems
Starting with a brief introduction of the mucoadhesive drug delivery systems, oral mucosa, and the theories of mucoadhesion, this article then proceeds to cover the works done so far in the field ...
https://journal.pda.org/content/66/5/466
Since the early 1980s the concept of mucoadhesion has gained considerable interest in pharmaceutical technology. The various advantages associated with these systems made buccal drug delivery as a novel route of drug administration. It prolongs the residence time of the dosage form at the site of application. These systems remain in close contact with the absorption tissue, the mucous membrane ...
https://freepaper.me/downloads/abstract/10.1081/DDC-52073
Oral Bioadhesive Drug Delivery Systems. The oral mucosal cavity is a feasible, safe, and very attractive site for drug delivery with good acceptance by users. The mucosa is relatively permeable and robust, shows short recovery times after stress or damage, is tolerant to potential allergens, and has a rich blood supply.
http://www.authorstream.com/Presentation/Alkesh_1988-1616939-bioadhesive-drug-delivery-system/
The buccal mucosa is less permeable compared to other oral drug delivery systems and is unable to retain dosage forms at the site of absorption. The use of bioadhesive polymers in buccal drug delivery systems allows a better retention of a dosage form …
http://www.scielo.br/pdf/bjps/v46n1/02.pdf
led drug delivery systems using bioadhesive molecules include a decrease in drug administration frequency and an increase in patient compliance to the therapy (Woodley, 2001). Therefore, a bioadhesive system controlling drug release could improve the treatment of diseases, helping to maintain an effective concentration of the drug at the
https://www.nature.com/articles/nrd.2018.183
Nov 30, 2018 · The requirement for delivery by injection is currently a limitation for the use of biologic drugs such as antibodies. In this Review, Mitragotri and colleagues discuss advances made in non ...
https://www.sciencedirect.com/science/article/pii/S1740674905000065
Mucoadhesive systems in oral drug delivery promise the advantage of a prolonged gastric or small intestinal residence time, an intimate contact of the delivery system with the absorption membrane and the basis for interactions of multifunctional polymers with the mucosa such as permeation enhancement or enzyme inhibition.
https://japer.in/storage/models/article/wNpf3chMfN15jmoxMAGlq9nP2e1ZbzPjRPHnmG9j83MqvOc9538I2jYaD2DA/mucoadhesive-buccal-drug-delivery-an-overview.pdf
per oral administration for systemic drug delivery. Mucoadhesion is define as drug delivery system that utilize the property of bioadhesion of certain water-soluble polymers which become adhesive on hydration and hence can be used for targeting a drug to a particular region of the body for an extended period of time. [2] The transmucosal ...
https://www.imedpub.com/articles/a-comprehensive-review-on-buccal-drug-delivery-system.pdf
A Comprehensive Review on Buccal Drug Delivery System ... Bioadhesive Delivery of Drug System in Oral Cavity 1. Sublingual delivery ... Which is drug delivery into the oral cavity?. Overview of the Oral Mucosa4, 5 A. Structure The oral mucosa is composed of outermost layer of stratified epithelium. Below lies a basement membrane, a lamina ...
https://pharmawiki.in/ppt-evaluation-of-oral-controlled-drug-delivery-systems/
Jan 13, 2014 · Contents of the powerpoint on Evaluation of Oral Controlled drug delivery systems include: INTRODUCTION ADVANTAGES AND DISADVANTAGES ATTRIBUTES OF DRUG CANDIDATE FOR CONTROLLED RELEASE SYSTEMS INVITRO-INVIVO EVALUATION OF FLOATING DRUG DELIVERY SYSTEM BIOADHESIVE DRUG DELIVERY SYSTEM BUCCAL BIOADHESIVE DRUG DELIVERY SYSTEM COLON SPECIFIC DRUG DELIVERY SYSTEM …
https://www.slideshare.net/optimpharma/bio-adhesive-drug-delivery-system
Mar 01, 2012 · Bio Adhesive Drug Delivery System 1. ... Bioadhesive polymers as platforms for oral controlled drug delivery: method to study bioadhesion. Int J Pharm, 1984; 19: 107–127.o Smart JD, Kellaway IW, Worthington HEC. An in vitro investigation of mucosa-adhesive materials for use in controlled drug delivery…
https://www.researchgate.net/publication/43561170_Bioadhesive_Polymeric_Platforms_for_Transmucosal_Drug_Delivery_Systems_-_a_Review
Transmucosal routes of drug delivery (i.e., the mucosal linings of the nasal, rectal, vaginal, ocular, and oral cavity) offer distinct advantages over peroral administration for systemic drug ...
https://farmacists.blogspot.com/2009/05/buccal-bioadhesive-drug-delivery.html
May 15, 2009 · In oral drug delivery, the drug absorption is limited by the gastrointestinal transit time of the dosage form. Since many drugs are absorbed only from the upper small intestine, localizing oral drug delivery systems in the stomach or duodenum, would significantly improve the extent of drug …
https://www.pharmatutor.org/pdf_download/pdf/Vol.%202,%20Issue%205,%20May%202014,%20PharmaTutor,%20Paper-7.pdf
BIOADHESIVE DELIVERY OF DRUG SYSTEM IN ORAL CAVITY Sublingual delivery, which is systemic delivery of drugs through the mucosal membrane lining the floor of the mouth, Buccal delivery, which is drug administration through the mucosal membranes lining the cheeks (buccal mucosa), and Local delivery, which is drug delivery into the oral cavity.[1]
https://tspace.library.utoronto.ca/bitstream/1807/60436/1/pr10012.pdf
Consequently, bioadhesive polymers have extensively been employed in transmucosal drug delivery systems. If these materials are then incorporated into pharmaceutical formulations, drug absorption by mucosal cells may be enhanced or the drug may be released at the site for an extended period of time.
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