Optimal Nanoparticle Size For Drug Delivery

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Drug delivery and nanoparticles: Applications and hazards

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
    Although solid NPs may be used for drug targeting, when reaching the intended diseased site in the body the drug carried needs to be released. So, for drug delivery biodegradable nanoparticle formulations are needed as it is the intention to transport and release the drug in order to be effective.Author: Wim H De Jong, Paul Ja Borm

Applications of nanoparticle systems in drug delivery ...

    https://www.sciencedirect.com/science/article/pii/S1319016417301792
    An ideal nanoparticle drug delivery system should be able to reach, recognized, bind and deliver its load to specific pathologic tissues, and minimize or avoids drug induced damage to healthy tissues.Thus, coating specific targeting ligand(s) on the surface of nanoparticles is the most common strategy.Author: Syed A.A. Rizvi, Ayman M. Saleh

Nanoparticles as a Drug Delivery System

    https://www.medscape.com/viewarticle/770397_4
    Nov 04, 2019 · This article summarizes recent developments in the use of nanoparticles as drug delivery systems. News & Perspective ... it was reported that a diameter of 50 nm is the optimal …

Nanoparticle-based targeted drug delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
    Nanoparticle Delivery Systems. Nanocapsules are vesicular systems in which a drug is confined to a cavity surrounded by a polymer membrane, whereas nanospheres are matrix systems in which the drug is physically and uniformly dispersed.Author: Rajesh Singh, James W. Lillard, James W. Lillard

Nanoparticles for drug delivery: The need for precision in ...

    https://www.sciencedirect.com/science/article/pii/S0939641107002895
    Nanoparticles for drug delivery: The need for precision in reporting particle size parameters. ... To underline the major role of nanoparticle size, the difficulties of obtaining accurate measurements of size will be first highlighted. A search of the literature, it becomes obvious that thorough size determination is frequently missing, leading ...Author: Marie Gaumet, Angelica Vargas, Robert Gurny, Florence Delie

Design Optimization of Tumor Vasculature-Bound ...

    https://www.nature.com/articles/s41598-018-35675-y
    Dec 11, 2018 · The optimal nanoparticle size that maximizes TNP is d ... This work lays a foundation to quantitatively evaluate preclinical nanoparticle-based drug delivery trials and support decisions in ...Author: Ibrahim M. Chamseddine, Hermann B. Frieboes, Michael Kokkolaras

Nano-enabled Drug Targeting & Delivery Technology - NVIGEN

    https://www.nvigen.com/drug-targeting-and-nanoparticle-drug-delivery/
    NVIGEN nanoparticle drug delivery platform is based on all clinically validated component materials. Nanoparticle size, shape, surface, and drug loading could all be tuned to achieve optimal drug pharmacokinetics, biodistribution, and cancer targeting and treatment efficacy.

Therapeutic Nanoparticles for Drug Delivery in Cancer ...

    https://clincancerres.aacrjournals.org/content/14/5/1310
    Mar 01, 2008 · Cancer nanotherapeutics are rapidly progressing and are being implemented to solve several limitations of conventional drug delivery systems such as nonspecific biodistribution and targeting, lack of water solubility, poor oral bioavailability, and low therapeutic indices. To improve the biodistribution of cancer drugs, nanoparticles have been designed for optimal size and surface ...Author: Kwangjae Cho, Kwangjae Cho, Xu Wang, Shuming Nie, Zhuo (Georgia) Chen, Dong M. Shin

Optimal particle size for anticancer nanomedicines discovered

    https://www.sciencedaily.com/releases/2014/10/141015165605.htm
    Oct 15, 2014 · Nanomedicines consisting of nanoparticles for targeted drug delivery to specific tissues and cells offer new solutions for cancer diagnosis and therapy. ... Optimal particle size for anticancer ...

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