We have collected information about Ophthalmic Drug Delivery System Challenges And Approaches for you. Follow the links to find out details on Ophthalmic Drug Delivery System Challenges And Approaches.
https://pdfs.semanticscholar.org/08b6/baa0191e3b8897422fd12be1ae7e9a0f12c1.pdf
Ophthalmic drug delivery is one of the most interesting and challenging endeavors facing the pharmaceutical scientist. The anatomy, physiology, and biochemistry of the eye render this organ highly impervious to foreign substances. Drug delivery to the eye can be broadly classified into anterior and posterior segments [Figure 1].
https://www.researchgate.net/publication/269967538_Ophthalmic_drug_delivery_system_Challenges_and_approaches
The main aim of this review is to focus on the various kinds of approaches which are used in ophthalmic drug delivery. Ophthalmic drug delivery system is used to treat various conditions ...
http://www.thepharmajournal.com/archives/2012/vol1issue4/PartA/4.pdf
Ocular drug delivery is hampered by the barriers protecting the eye. The bioavailability of the active drug substance is often the major hurdle to overcome. Conventional ocular dosage form, including eye drops, are no longer sufficient to combat ocular diseases.Author: K. P. Sampath Kumar, Debjit Bhowmik, Shravan Paswan, Shweta Srivastava
https://www.aao.org/eyenet/article/novel-approaches-to-drug-delivery-2
On the invention side, he described the challenge of creating something to treat a disease that requires chronic therapy. “There is limited space in the eye. So the size of a drug delivery system is limited by the duration of treatment, the potency of the molecule, and its duration of action.
http://jpet.aspetjournals.org/content/early/2019/05/09/jpet.119.256933
Jan 01, 2019 · An ideal drug delivery system should be designed to enhance drug bioavailability, provide controlled and sustained release of drug at site of action and overcome various ocular barriers. Conventional ophthalmic medications includes the use of topical eye drops and intravitreal injections of anti-VEGF agent for treatment of anterior and posterior segment disorders respectively.Author: Vrinda Gote, Sadia Sikder, Jeff Sicotte, Dhananjay Pal
https://www.mdpi.com/journal/pharmaceutics/special_issues/ophthalmic_drugdelivery
In this study, we designed a novel sustained-release drug delivery system (DDS) for dry eye therapy by rebamipide nanoparticles. The rebamipide solid nanoparticle-based ophthalmic formulation (REB-NPs) was prepared by a bead mill using additives (2-hydroxypropyl-β-cyclodextrin and methylcellulose) and a gel base (carbopol).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061492/
Topical instillation of ophthalmic drops is the most common method used to administer pharmaceutical agents for ocular disease; 90% of ophthalmic drug formulations are for topical drop use. Methods of topical drug delivery include eye drops, ointments, suspensions, contact lenses, and some drug delivery devices.Author: Henry F. Edelhauser, Cheryl L. Rowe-Rendleman, Michael R. Robinson, Daniel G. Dawson, Gerald J. Chad...
https://link.springer.com/chapter/10.1007/978-3-319-29346-2_8
Nov 13, 2016 · Additionally, the design approaches for the modified ocular drug delivery such as ocular implants, inserts, lenses, and ocular shields are described with respect to the formulation development. Finally, ocular drug delivery systems that are relatively newer or employed less frequently such as intravitreal injections, ocular iontophoresis, etc. are discussed.Author: Vivek S. Dave
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
The major challenge faced by today’s pharmacologist and formulation scientist is ocular drug delivery. Topical eye drop is the most convenient and patient compliant route of drug administration, especially for the treatment of anterior segment diseases.Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
Searching for Ophthalmic Drug Delivery System Challenges And Approaches?
You can just click the links above. The data is collected for you.
