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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
Several liposomal formulations for ocular drug delivery are being exploited, few are in pre-clinical and clinical study stage and few are commercially available. Visudyne ® and Tears again ® are the examples of commercially available liposomal formulations for the treatment of ocular diseases.Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781321/
Sep 06, 2019 · For quite a few decades, the mechanism of specific drug delivery to ocular milieu was indeed a challenge [201,202]. The common pharmaceutical formulations applied to this purpose, drugs applied as eye drops, suffered downsides which, by turn, required the implementation of distinct carriers aimed in ocular administration route.Author: Eliana B. Souto, João Dias-Ferreira, Ana López-Machado, Miren Ettcheto, Amanda Cano, Antonio Camins ...
https://journals.sagepub.com/doi/pdf/10.1177/0192623307310955
Vol. 36, No. 1, 2008 OCULAR DRUG DELIVERY FORMULATIONS 51 FIGURE 3.—Sites and methods for ocular drug delivery to the eye. Various methods for delivery of drugs to the anterior and posterior chambers of the eye are illustrated, including sites for conventional drug delivery as well as newer routes. Reproduced by permission from Davis et al ...
https://www.sciencedirect.com/science/article/pii/S1359644618303994
Ocular drug delivery is a field in which regular ADME tools are not useful. • Pharmacokinetics based dosing aid for ocular drug delivery is presented. • User-friendly dosing aid guides early stage design of delivery systems. • Guidance for the delivery route, dosing and formulation design is presented.Author: Astrid Subrizi, Astrid Subrizi, Eva M. del Amo, Viktor Korzhikov-Vlakh, Tatiana Tennikova, Marika Ru...
https://journals.sagepub.com/doi/full/10.1177/0192623307310955
Jan 01, 2008 · Novel ocular drug-delivery formulations and methods for localized, sustained delivery may provide the solution for treating serious intraocular diseases. Although regulatory guidance is sparse for ocular drugs, review of FDA Pharmacology Reviews and selected literature can provide insights.Author: Brian G. Short
https://www.researchgate.net/publication/225897418_OCULAR_DRUG_DELIVERY_SYSTEM_-_A_REVIEW
OCULAR DRUG DELIVERY SYSTEM – A REVIEW. ... Conventional ophthalmic formulations like solution, suspension, and ointment have many disadvantages which …
https://www.allfordrugs.com/ocular-drug-delivery-systems-an-overview/
The development of an ophthalmic drug delivery system based on cyclodextrins is relatively recent, occurring in the Patel GM, et al.: Advances and challenges in ocular drug delivery system early 1990s. Cyclodextrins were introduced in ocular drug formulations initially with the aim of increasing the solubility of lipophilic drugs in solution.
https://www.researchgate.net/publication/235924442_OCULAR_DRUG_DELIVERY_A_REVIEW
OCULAR DRUG DELIVERY: A REVIEW ... Such a drug delivery can be achieved by designing formulations such as microspheres, nanoparticles, liposomes which …
https://innovareacademics.in/journal/ijpps/Vol2Issue4/434.pdf
Amongst the various routes of drug delivery, the field of ocular drug delivery is one of the most interesting and challenging endeavors facing the pharmaceutical scientist for past 10‐20 years1. As an isolated organ, eye is very difficult to study from a drug delivery point of view. Despite these
https://www.sciencedirect.com/science/article/pii/0169409X9500012V
advanced drug delivery ELSEVIER reviews Advanced Drug Delivery Reviews 16 (1995) 39-43 Ocular drug delivery conventional ocular formulations John C. Lang Alcon Laboratories. Inc., 6201 S. Freeway.Author: John C. Lang
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