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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
http://samples.jbpub.com/9781284025682/9781449674250_CH10.pdf
Ocular Drug Delivery AswAni Dutt VADlApuDi, Kishore CholKAr, supriyA reDDy DAsAri, AnD Ashim K. mitrA CHAPTER OBJECTIVES Upon completing this chapter, the reader should be able to Describe the anatomy and physiology of the eye. Understand the importance of various routes of drug administration to the eye. Describe various barriers to ocular drug delivery and constraints with
https://www.researchgate.net/publication/225897418_OCULAR_DRUG_DELIVERY_SYSTEM_-_A_REVIEW
A successful design of a drug delivery system, therefore, requires an integrated knowledge of the drug molecule and the constraints offered by the ocular route of administration [3].
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
To overcome the ocular drug delivery barriers and improve ocular bioavailability, various conventional and novel drug delivery systems have been developed such as emulsion, ointments, suspensions, aqueous gels, nanomicelles, nanoparticles, liposomes, dendrimers, implants, contact lenses, nanosuspensions, microneedles, and in situ ...Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
https://www.arvo.org/globalassets/annual-meeting/program/education-courses/2020-agenda---ocular-drug-delivery.pdf
Ocular drug delivery: Fundamentals, challenges, and technologies Organizers Ash Jayagopal, PhD, Kodiak Sciences Inc. and Uday Kompella, PhD, University of Colorado, Anschutz Medical Campus Description Ocular drug delivery is an evolving field featuring cutting-edge advances in devices, formulations, and paradigms for design and characterization.
https://www.researchgate.net/publication/235924442_OCULAR_DRUG_DELIVERY_A_REVIEW
PDF The route of choice for the treatment of ophthalmic diseases is by the topical route because of the blood ocular barrier. ... OCULAR DRUG DELIVERY: A REVIEW . Palani S ... polymeric micelle ...
http://www.authorstream.com/Presentation/priyadebnath-1542656-ocular-drug-delivery-system/
Sep 17, 2012 · INTRODUCTION Ocular administration of drug is primarily associated with the need to treat ophthalmic diseases. Eye is the most easily accessible site for topical administration of a medication. Ideal ophthalmic drug delivery must be able to sustain the drug release and to remain in the vicinity of front of the eye for prolong period of time.
https://kundoc.com/pdf-designing-dendrimers-for-ocular-drug-delivery-.html
In this paper we report the synthesis of a new series of phosphorus-containing dendrimers, and attempts to use them for the ocular delivery of a drug to treat glaucoma [43] and ocular hypertension, which are among the most frequent and severe ocular diseases, susceptible to degenerate to blindness [44].
https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-delivery-system
Drug Delivery System. A drug delivery system (DDS) is defined as a formulation or a device that enables the introduction of a therapeutic substance into the body and improves its efficacy and safety by controlling the rate, time, and place of release of drugs in the body.
http://jpet.aspetjournals.org/content/370/3/602
Sep 01, 2019 · Ocular drug delivery has always been a challenge for ophthalmologists and drug-delivery scientists due to the presence of various anatomic and physiologic barriers. Inimitable static and dynamic ocular barriers not only exclude the entry of xenobiotics but also discourage the active absorption of therapeutic agents. Designing an ideal delivery scheme should include enhanced drug ...Author: Vrinda Gote, Sadia Sikder, Jeff Sicotte, Dhananjay Pal
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