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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834906/
Mar 08, 2012 · 2. Ocular Drug Delivery. Current innovation in glaucoma treatment is focused on the improvement of drug delivery methods. The aim is to deliver drugs locally in a controlled manner while mitigating the challenge of poor patient adherence, compliance, and persistence.Author: Nathan Gooch, Sarah A. Molokhia, Russell Condie, Randon Michael Burr, Bonnie Archer, Balamurali K. A...
https://www.mdpi.com/1999-4923/4/1/197/pdf
Ocular Drug Delivery. Current innovation in glaucoma treatment is focused on the improvement of drug delivery methods. The aim is to deliver drugs locally in a controlled manner while mitigating the challenge of poor patient adherence, compliance, and persistence.Author: Nathan Gooch, Sarah A. Molokhia, Russell Condie, Randon Michael Burr, Bonnie Archer, Balamurali K. A...
https://www.mdpi.com/1999-4923/4/1/197
Current glaucoma management modalities are hindered by low patient compliance and adherence. This can be due to highly complex treatment strategies or poor patient understanding. Treatments focus on the management or reduction of intraocular pressure. This is most commonly done through the use of daily topical eye drops.Author: Nathan Gooch, Sarah A. Molokhia, Russell Condie, Randon Michael Burr, Bonnie Archer, Balamurali K. A...
https://www.researchgate.net/publication/259153351_Ocular_Drug_Delivery_for_Glaucoma_Management
Ocular Drug Delivery for Glaucoma Management Nathan Gooch 1 , Sarah A. Molokhia 2 , Russell Condie 1 , Randon Michael Burr 3 , Bonnie Archer 3 , Balamurali K. Ambati 3 and Barbara Wirostko 3, *
http://www.smgebooks.com/glaucoma/chapters/GLC-16-05.pdf
hydrogels in addition to, colloidal carriers as liposomes, lipid nanoparticles, niosomes and polymeric nanoparticles. These delivery systems aim at increasing the ocular bioavailability and clinical efficacy of anti-glaucoma drugs and proved to be advantageous compared to eye drops.
https://www.glaucoma.org/treatment/new-medication-delivery-systems-for-glaucoma.php
The basic idea of drug delivery systems for glaucoma is to apply, insert, or inject medication to the eye that will release over weeks or months. Various delivery approaches are being developed that can be categorized as: on the eye, in the eye, and around the eye.
https://www.reviewofoptometry.com/article/reinventing-glaucoma-therapy
Clearside Biomedical and Santen are collaborating on supraciliary drug delivery in glaucoma via Clearside’s microinjector and Santen’s sustained-release formulations. Injection into the supraciliary space puts the drug in close proximity to the ciliary body—the targeted tissue of most glaucoma meds.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770064/
Since the goal of drug delivery in glaucoma management is to improve therapeutic efficacy while minimizing systemic and local toxicity; it is very important to optimize the process of drug loading and ocular release parameters to avoid dose dumping or erratic drug release profiles.Author: Dharani Manickavasagam, Moses O. Oyewumi
https://www.glaucoma.org/treatment/alternative-drug-delivery-systems-for-glaucoma.php
New and novel proposals for glaucoma drug delivery were the topic of a session at the Glaucoma 360 New Horizons Forum in San Francisco (presented by Glaucoma Research Foundation). The session highlighted a variety of amazing new technologies that we hope will soon become available to improve the medical therapy of glaucoma.
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