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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
To overcome the ocular drug delivery barriers and improve ocular bioavailability, various conventional and novel drug delivery systems have been developed such as emulsion, ointments, suspensions, aqueous gels, nanomicelles, nanoparticles, liposomes, dendrimers, implants, contact lenses, nanosuspensions, microneedles, and in situ ...Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
https://www.researchgate.net/publication/225897418_OCULAR_DRUG_DELIVERY_SYSTEM_-_A_REVIEW
OCULAR DRUG DELIVERY SYSTEM – A REVIEW ... Ideal ophthalmic drug delivery must be able to sustain the drug release and to remain in the vicinity of front of the eye for prolong period of time ...
http://samples.jbpub.com/9781284025682/9781449674250_CH10.pdf
Ocular Drug Delivery AswAni Dutt VADlApuDi, Kishore CholKAr, supriyA reDDy DAsAri, AnD Ashim K. mitrA CHAPTER OBJECTIVES Upon completing this chapter, the reader should be able to Describe the anatomy and physiology of the eye. Understand the importance of various routes of drug administration to the eye. Describe various barriers to ocular drug delivery and constraints with
https://www.slideshare.net/vijayalakshmikalaga/ocular-drug-delivery-systems
Sep 17, 2012 · ocular drug delivery systems 1. INTRODUCTION Ocular administration of drug isprimarily associated with the need totreat ophthalmic diseases. Eye is the most easily accessible site fortopical administration of a medication. Ideal ophthalmic drug delivery mustbe able to sustain the drug release andto remain in the vicinity of front of theeye for prolong period of time.
https://www.ijpbs.com/ijpbsadmin/upload/ijpbs_50c8546501de1.pdf
delivery. Drug delivery to eye has always been a daunting task in the field of pharmaceutical research due to unique anatomy and physiology of the eye. One of the major problems encountered by conventional ocular dosage forms include rapid precorneal drug loss due to nasolacrimal drainage, tear turnover and drug dilution resulting in poor ...
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