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https://journals.sagepub.com/doi/10.1177/153303460500400409
An attractive strategy that has gained importance in brain tumor therapy has relied on local and controlled delivery of chemotherapeutic agents by biodegradable polymers. This technique allows direct exposure of tumor cells to a therapeutic agent for a prolonged period of time and has been shown to prolong the survival of patients with malignant brain tumors.Author: Maciej S. Lesniak
https://journals.sagepub.com/doi/pdf/10.1177/153303460500400409
mer based drug delivery methods for use in the treatment of malignant brain tumors. Introduction Malignant brain tumors are rare but one of the most aggressive of human cancers. According to the Central Brain Tumor Registry of the United States, the incidence rate of all primary benign and malignant brain tumors is 14 cases per 100,000 per-
https://www.scholars.northwestern.edu/en/publications/novel-advances-in-drug-delivery-to-brain-cancer
Systemic administration is often associated with toxic side effects and ultimately fails to achieve therapeutic concentrations within a tumor. An attractive strategy that has gained importance in brain tumor therapy has relied on local and controlled delivery of chemotherapeutic agents by biodegradable polymers.Author: Maciej S. Lesniak
https://www.researchgate.net/publication/7716054_Novel_Advances_in_Drug_Delivery_to_Brain_Cancer
Novel Advances in Drug Delivery to Brain Cancer Article · Literature Review in Technology in cancer research & treatment 4(4):417-28 · September 2005 with 9 Reads How we measure 'reads'
https://www.sciencedirect.com/science/article/pii/S1773224719302163
Nanotechnology-based novel drug delivery systems Nanotechnology-based therapeutics is highly used in cancer therapy for enhancing drug solubility, stability, and decreasing multidrug resistance as well as to enhance the safety and efficacy of cancer treatment.Author: Umme Hani, Mohamed Rahamathulla, Riyaz Ali Osmani, Honnavalli Yogish Kumar, Deeparani Urolagin, Moha...
https://www.sciencedirect.com/science/article/pii/S1773224719313097
Tumor microenvironment based drug delivery still demands advances for the effective treatment of cancer. Various stimuli responsive liposomes can lead to preferential release of the drug in response to particular stimuli such as temperature, pH, redox, and hypoxia resulting in improvement in the therapeutic efficacy.Author: Shivani Saraf, Ankit Jain, Ankita Tiwari, Amit Verma, Pritish Kumar Panda, Sanjay K. Jain
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269656/
In this article, we summarize recent progress in drug delivery to the brain, with an emphasis on convection-enhanced delivery of nanocarriers. We examine the potential of new delivery methods to permit novel drug- and gene-based therapies that target brain cancer stem cells (BCSCs) and discuss the use of nanomaterials for imaging of tumors and drug delivery.
https://link.springer.com/article/10.1007%2Fs40263-016-0405-9
Jan 18, 2017 · This is a pronounced challenge for the pharmaceutical fraternity. Hence, in addition to the discovery of novel entities and drug candidates, scientists are also developing new formulations of existing drugs for brain targeting. Several approaches have been investigated to allow therapeutics to cross the BBB.Author: Mayur M. Patel, Bhoomika M. Patel
https://www.nature.com/articles/s41392-017-0004-3
Mar 16, 2018 · Novel drug delivery systems promise a bright future for cancer treatment in the next decade or so; they might become major arsenal for safer and more efficient treatments by ensuring proper drug ...Author: Sudipta Senapati, Arun Kumar Mahanta, Sunil Kumar, Pralay Maiti
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Working backwards is sometimes an effective way to solve a problem. In drug delivery research, this means starting with a delivery method. The target may be whole organs (heart, lung, brain), tissue types (muscle, nerve), disease-specific structures (tumor cells), or structures inside of cells.
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